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Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches

Aging Cell(2025)10.1111/acel.70114Source: DataRank Database

Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches is a research paper published in Aging Cell (2025). On theSindex it has a DataRank of 0. It has been cited 11 times.

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Open Access11 citations

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Enrichment:Funding (8 grants)Impact (FWCI 7.77)OA: goldTopics (47)IDs (PubMed, PMC, OpenAlex)Annotations (1)

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Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Sophia Mahoney ORCID,Katelyn R. Ludwig ORCID,Jill Miyamoto-Ditmon,Nicholas S. VanDongen,Nirad Banskota ORCID

Live enrichment

PubMed:40437670 PMC:PMC12341784 OpenAlex:https://openalex.org/W4410808013

National Institutes of Health

Grant: F31HL165885

National Institutes of Health

Grant: F32HL167552

National Institutes of Health

Grant: R01AG055822

National Institutes of Health

Grant: R01AG055822‐04S1

American Heart Association

Grant: 23CDA1053582

American Heart Association

Grant: 23POST1025630

NHLBI NIH HHS

Grant: K99 HL159241

NIH HHS

Grant: R01AG055822-04S1

FWCI

7.77

Citation Percentile

1.0%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.70114

publisherhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/acel.70114

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.70114

journalhttps://doi.org/10.1111/acel.70114

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40437670

Fields of Study

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model OrganismsCircadian rhythm and melatoninFlavonolsAnimalsCellular SenescenceMuscle, SkeletalMiceAgingSenotherapeuticsMaleDietary SupplementsMice, Inbred C57BLFlavonoidsHand Strength

MeSH Terms

SenotherapeuticsAgingAnimalsFlavonoidsMaleMice, Inbred C57BLCellular SenescenceMuscle, SkeletalHand StrengthDietary SupplementsFlavonolsMice

Keywords

FisetinSenescenceGrip strengthSkeletal muscleBiologyTranscriptomeInternal medicineEndocrinologyCell biologyMedicinePhysiologyBiochemistryGene expressionGeneFlavonoidAntioxidantMotor functionSenescence Associated Secretory PhenotypeNatural SenolyticSkeletal Muscle Senescence

Intermittent Supplementation With Fisetin Improves Physical Function and Decreases Cellular Senescence in Skeletal Muscle With Aging: A Comparison to Genetic Clearance of Senescent Cells and Synthetic Senolytic Approaches

FAIR Checklist

Authors (11)

Funding (8 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)