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The alpha‐7 nicotinic acetylcholine receptor agonist GTS ‐21 engages the glucagon‐like peptide‐1 incretin hormone axis to lower levels of blood glucose in db/db mice

Diabetes Obesity and Metabolism(2022)10.1111/dom.14693Source: DataRank Database

The alpha‐7 nicotinic acetylcholine receptor agonist GTS ‐21 engages the glucagon‐like peptide‐1 incretin hormone axis to lower levels of blood glucose in db/db mice is a research paper published in Diabetes Obesity and Metabolism (2022). On theSindex it has a DataRank of 0. It has been cited 12 times.

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Open Access12 citations

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Enrichment:Funding (6 grants)OA: greenTopics (51)IDs (PubMed, PMC)Annotations (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Oleg G. Chepurny ORCID,Colin A. Leech ORCID,Napat Pruekprasert,Megan E. Molnar ORCID,James J. Collier

Live enrichment

PubMed:35293666 PMC:PMC9177741

National Institutes of Health

Grant: R01DK069575

National Institutes of Health

Grant: R01DK122332

NIDDK NIH HHS

Grant: R01 DK123183

National Institutes of Health

Grant: 5R01DK069575-04

Molecular Basis of Antidiabetogenic Hormone Action

National Institutes of Health

Grant: 1R01DK122332-01A1

Alpha7 Nicotinic Acetylcholine Receptor Regulation of Glucagon-Like Peptide- 1 Incretin Hormone Action.

National Institutes of Health

Grant: 1R01DK123183-01A1

SGK1 is a regulator of islet beta cell mass and secretory function

greenLicense: Wiley Online Library User Agreement

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9177741

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1111/dom.14693

publisherhttps://onlinelibrary.wiley.com/doi/full-xml/10.1111/dom.14693

publisherhttps://dom-pubs.pericles-prod.literatumonline.com/doi/pdf/10.1111/dom.14693

https://doi.org/10.1111/dom.14693

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsMice, KnockoutHumansMiceDiabetes Mellitus, Type 2Insulin ResistanceBenzylidene CompoundsPyridinesGastric Inhibitory PolypeptideGlucagonInsulinBlood GlucoseTyrosineNicotinic AgonistsGlucose Tolerance TestFemaleMaleGlucagon-Like Peptide 1Incretinsalpha7 Nicotinic Acetylcholine ReceptorSitagliptin PhosphateGlucagon-Like Peptide-1 Receptor

Keywords

GIPGlp-1NeuropharmacologyDpp-4 InhibitorGlycaemic ControlAntidiabetic DrugBlood GlucoseMaleMice, KnockoutPyridinesSitagliptin PhosphateGastric Inhibitory PolypeptideGlucose Tolerance TestGlucagonBenzylidene CompoundsIncretinsGlucagon-Like Peptide-1 ReceptorMiceDiabetes Mellitus, Type 2Glucagon-Like Peptide 1AnimalsHumansInsulinFemaleNicotinic AgonistsInsulin Resistance