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Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4+ helper and CD8+ effector T cells

Immunology and Cell Biology(2023)10.1111/imcb.12651Source: DataRank Database

Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4+ helper and CD8+ effector T cells is a research paper published in Immunology and Cell Biology (2023). On theSindex it has a DataRank of 0. It has been cited 6 times.

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Open Access6 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 0.55)OA: greenTopics (41)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Lauren Appell,Lyle Burdine ORCID,Lora J. Rogers,Lauren C. Morehead ORCID,Daniel Fil

Live enrichment

PubMed:37149747 PMC:PMC10527493 OpenAlex:https://openalex.org/W4375846153

NIH HHS

Grant: DP5 OD031863

NIAID NIH HHS

Grant: R21 AI173759

NIGMS NIH HHS

Grant: P20 GM121293

FWCI

0.55

Citation Percentile

0.6%

Citation Trend

2023

2024

2025

2026

greenLicense: http://onlinelibrary.wiley.com/termsAndConditions#vor

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10527493/pdf/nihms-1907673.pdf

publisherhttps://onlinelibrary.wiley.com/doi/pdf/10.1111/imcb.12651

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10527493

journalhttps://doi.org/10.1111/imcb.12651

Fields of Study

Immune Cell Function and InteractionT-cell and B-cell ImmunologyCAR-T cell therapy researchHumansAnimalsMiceDNA-Activated Protein KinaseCD8-Positive T-LymphocytesAntineoplastic AgentsCD4-Positive T-LymphocytesDNA

MeSH Terms

AnimalsAntineoplastic AgentsDNAHumansCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesMiceDNA-Activated Protein Kinase

Keywords

Immune systemCytotoxic T cellCancer researchIL-2 receptorT cellCD8ImmunotherapyBiologyCancer immunotherapyChemistryCell biologyImmunologyMolecular biologyIn vitroBiochemistryCytotoxicityCd8+ Effector T CellsDna Dependent Protein Kinase Catalytic SubunitT Cell MetabolismCd4+ Helper T CellsOtisiinfekl-mc38Nu7441t Cell Activation

Sustainable Development Goals

SDG 0: Good health and well-being