Semliki Forest virus strongly reduces mosquito host defence signaling is a research paper published in Insect Molecular Biology (2008). On theSindex it has a DataRank of 3.0. It has been cited 93 times, with 77 citing works in its 1-hop citation network.
Abstract The Alphavirus genus within the Togaviridae family contains several important mosquito‐borne arboviruses. Other than the antiviral activity of RNAi, relatively little is known about alphavirus interactions with insect cell defences. Here we show that Semliki Forest virus (SFV) infection of Aedes albopictus‐ derived U4.4 mosquito cells reduces cellular gene expression. Activation prior to SFV infection of pathways involving STAT/IMD, but not Toll signaling reduced subsequent virus gene expression and RNA levels. These pathways are therefore not only able to mediate protective responses against bacteria but also arboviruses. However, SFV infection of mosquito cells did not result in activation of any of these pathways and suppressed their subsequent activation by other stimuli.
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Base Score Contribution
0.681
From this paper's citation signal
Citation Network Contribution
2.3
From 64 citing papers with measurable signal
Ranked by citation count — the same ordering the engine uses when summing log1p(Cq) over citers.
DataRank blends this paper's own citation count with the influence of the papers that cite it. Here, roughly 23% comes from its base citations and 77% from the citation network (64 citing papers contributed measurable signal).
Citers are pulled from OpenAlex sorted by cited_by_count:descand capped per paper, so when the cap binds we keep the highest-signal references and the score is reproducible across reruns.
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