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BCRP/ABCG2 Transporter Regulates Accumulation of Cadmium in Kidney Cells: Role of the Q141K Variant in Modulating Nephrotoxicity

Drug Metabolism and Disposition(2021)10.1124/dmd.121.000446Source: DataRank Database

BCRP/ABCG2 Transporter Regulates Accumulation of Cadmium in Kidney Cells: Role of the Q141K Variant in Modulating Nephrotoxicity is a research paper published in Drug Metabolism and Disposition (2021). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 0.67)OA: bronzeTopics (33)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (7)

Danielle Kozlosky ORCID,Ranran Zhang ORCID,Cathleen Doherty ORCID,Brian Buckley ORCID,Emily S. Barrett ORCID

Live enrichment

PubMed:34074729 PMC:PMC8382159 OpenAlex:https://openalex.org/W3164181803

NIEHS NIH HHS

Grant: R01 ES029275

NIEHS NIH HHS

Grant: P30 ES005022

NIEHS NIH HHS

Grant: F31 ES032319

NCATS NIH HHS

Grant: UL1 TR003017

NIEHS NIH HHS

Grant: T32 ES007148

FWCI

0.67

Citation Percentile

0.6%

Citation Trend

2022

2023

2024

2025

bronzeLicense: https://www.elsevier.com/legal/tdmrep-license

journalhttps://dmd.aspetjournals.org/content/dmd/49/8/629.full.pdf

publisherhttps://dmd.aspetjournals.org/content/dmd/49/8/629.full.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0090955624078449?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0090955624078449?httpAccept=text/plain

publisherhttps://syndication.highwire.org/content/doi/10.1124/dmd.121.000446

Fields of Study

Heavy Metal Exposure and ToxicityTrace Elements in HealthDrug Transport and Resistance Mechanisms

MeSH Terms

ATP Binding Cassette Transporter, Subfamily G, Member 2AnimalsBiological Transport, ActiveCadmiumHumansKidneyNeoplasm ProteinsApoptosisMice, KnockoutPolymorphism, Single NucleotideMiceHEK293 CellsRenal EliminationProtective Factors

Keywords

CadmiumChemistryToxicityATP-binding cassette transporterKidneyAbcg2EffluxNephrotoxicityIn vivoMolecular biologyTransporterBiologyBiochemistryGeneEndocrinologyGenetics