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CYP2C19 Plays a Major Role in the Hepatic N-Oxidation of Cotinine

Drug Metabolism and Disposition(2022)10.1124/dmd.121.000624Source: DataRank Database

CYP2C19 Plays a Major Role in the Hepatic N-Oxidation of Cotinine is a research paper published in Drug Metabolism and Disposition (2022). On theSindex it has a DataRank of 0. It has been cited 9 times.

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Open Access9 citations

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Enrichment:Funding (2 grants)Impact (FWCI 1.37)OA: hybridTopics (47)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Christy J.W. Watson ORCID,Gang Chen ORCID,Philip Lazarus ORCID,Yadira X. Pérez-Páramo ORCID

Live enrichment

PubMed:35197312 PMC:PMC9832378 OpenAlex:https://openalex.org/W4213421576

NIEHS NIH HHS

Grant: R01 ES025460

National Institutes of Health

Grant: 5R01ES025460-05

The UGT2A and 3A metabolizing enzymes and tobacco-related cancer risk

FWCI

1.37

Citation Percentile

0.8%

Citation Trend

2022

2023

2025

2026

hybridLicense: cc-by-nc

journalhttps://dmd.aspetjournals.org/content/dmd/51/1/29.full.pdf

publisherhttps://dmd.aspetjournals.org/content/dmd/51/1/29.full.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0090955624009036?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0090955624009036?httpAccept=text/plain

publisherhttps://syndication.highwire.org/content/doi/10.1124/dmd.121.000624

Fields of Study

Pharmacogenetics and Drug MetabolismSynthesis and Biological EvaluationNicotinic Acetylcholine Receptors Study0301 basic medicine0303 health sciences03 medical and health sciences0302 clinical medicine

MeSH Terms

CotinineCytochrome P-450 Enzyme SystemHumansKineticsLiverMicrosomes, LiverNicotineCytochrome P-450 CYP2E1Cytochrome P-450 CYP3AHEK293 CellsCytochrome P-450 CYP2B6Cytochrome P-450 CYP2C19

Keywords

CYP2A6CotinineMicrosomeCYP3A4ChemistryCYP2B6Cytochrome P450EnzymeCYP2E1MetabolismCYP1A2PharmacologyBiochemistryNicotineBiologyInternal medicineMedicineCytochrome P-450 CYP2E1ArticlesCytochrome P-450 CYP2C19KineticsCytochrome P-450 CYP2B6HEK293 CellsCytochrome P-450 Enzyme SystemLiverMicrosomes, LiverHumansCytochrome P-450 CYP3A

Sustainable Development Goals

SDG 3: 3. Good health

CYP2C19 Plays a Major Role in the Hepatic N-Oxidation of Cotinine

FAIR Checklist

Authors (4)

Funding (2 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)