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Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor-β/Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins)

Drug Metabolism and Disposition(2022)10.1124/dmd.121.000781Source: DataRank Database

Regulation of Blood-Brain Barrier Transporters by Transforming Growth Factor-β/Activin Receptor-Like Kinase 1 Signaling: Relevance to the Brain Disposition of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors (i.e., Statins) is a research paper published in Drug Metabolism and Disposition (2022). On theSindex it has a DataRank of 0. It has been cited 20 times.

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Open Access20 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (3 grants)Impact (FWCI 2.05)OA: bronzeTopics (51)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Wazir Abdullahi,Erica I. Williams ORCID,Jeffrey J. Lochhead ORCID,Hrvoje Brzica,Joshua A Stanton ORCID

Live enrichment

PubMed:35504656 PMC:PMC11022862 OpenAlex:https://openalex.org/W4225292367

NIEHS NIH HHS

Grant: R25 ES025494

NINDS NIH HHS

Grant: R01 NS084941

NIDA NIH HHS

Grant: R01 DA051812

FWCI

2.05

Citation Percentile

0.9%

Citation Trend

2022

2023

2024

2025

2026

bronzeLicense: https://www.elsevier.com/legal/tdmrep-license

journalhttps://dmd.aspetjournals.org/content/dmd/50/7/942.full.pdf

BRONZEhttps://dmd.aspetjournals.org/content/dmd/50/7/942.full.pdf

publisherhttps://dmd.aspetjournals.org/content/dmd/50/7/942.full.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0090955624008286?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0090955624008286?httpAccept=text/plain

Fields of Study

Caveolin-1 and cellular processesDrug Transport and Resistance MechanismsBone Metabolism and DiseasesMedicineATP Binding Cassette Transporter, Subfamily B, Member 1ATP Binding Cassette Transporter, Subfamily G, Member 2Activin ReceptorsAnimalsBlood-Brain BarrierBrainCoenzyme AEnzyme InhibitorsGrowth Differentiation Factor 2Hydroxymethylglutaryl-CoA Reductase InhibitorsNeoplasm ProteinsNeoplasmsOrganic Anion TransportersOxidoreductasesRatsTransforming Growth Factor betaTransforming Growth Factors

MeSH Terms

ATP Binding Cassette Transporter, Subfamily G, Member 2AnimalsBlood-Brain BarrierBrainCoenzyme AEnzyme InhibitorsNeoplasm ProteinsNeoplasmsOxidoreductasesTransforming Growth FactorsTransforming Growth Factor betaHydroxymethylglutaryl-CoA Reductase InhibitorsATP Binding Cassette Transporter, Subfamily B, Member 1Organic Anion TransportersActivin ReceptorsRatsGrowth Differentiation Factor 2

Keywords

Blood–brain barrierInternal medicineEndocrinologyPharmacologyStatinLRP1BiologyChemistryCentral nervous systemMedicineLDL receptorLipoproteinCholesterol

Sustainable Development Goals

SDG 0: Good health and well-being