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Pharmacokinetic Modeling of Warfarin І – Model-Based Analysis of Warfarin Enantiomers with a Target Mediated Drug Disposition Model Reveals CYP2C9 Genotype-Dependent Drug-Drug Interactions of S-Warfarin

Drug Metabolism and Disposition(2022)10.1124/dmd.122.000876Source: DataRank Database

Pharmacokinetic Modeling of Warfarin І – Model-Based Analysis of Warfarin Enantiomers with a Target Mediated Drug Disposition Model Reveals CYP2C9 Genotype-Dependent Drug-Drug Interactions of S-Warfarin is a research paper published in Drug Metabolism and Disposition (2022). On theSindex it has a DataRank of 0. It has been cited 15 times.

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Open Access15 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (2 grants)Impact (FWCI 2.05)OA: bronzeTopics (18)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Darcy R. Flora,Allan E. Rettie ORCID,Richard C. Brundage ORCID,Timothy S. Tracy,Shen Cheng

Live enrichment

PubMed:35798369 PMC:PMC9488981 OpenAlex:https://openalex.org/W4284711870

NIGMS NIH HHS

Grant: R01 GM069753

NIGMS NIH HHS

Grant: P01 GM032165

FWCI

2.05

Citation Percentile

0.9%

Citation Trend

2022

2023

2024

2025

2026

bronzeLicense: https://www.elsevier.com/legal/tdmrep-license

journalhttps://dmd.aspetjournals.org/content/dmd/50/9/1287.full.pdf

publisherhttps://dmd.aspetjournals.org/content/dmd/50/9/1287.full.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0090955624008614?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0090955624008614?httpAccept=text/plain

publisherhttps://syndication.highwire.org/content/doi/10.1124/dmd.122.000876

Fields of Study

Pharmacogenetics and Drug MetabolismComputational Drug Discovery MethodsReceptor Mechanisms and Signaling

Keywords

WarfarinCYP2C9PharmacologyPharmacokineticsDrug interactionDrugCytochrome P450ChemistryMedicineInternal medicineAtrial fibrillationMetabolismGenetic polymorphismdrug-drug interactionsPharmacokinetic Modeling

Sustainable Development Goals

SDG 0: Good health and well-being

Pharmacokinetic Modeling of Warfarin І – Model-Based Analysis of Warfarin Enantiomers with a Target Mediated Drug Disposition Model Reveals CYP2C9 Genotype-Dependent Drug-Drug Interactions of S-Warfarin

FAIR Checklist

Authors (5)

Funding (2 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)