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Inhibition of Colon Cancer Cell Growth by Phosphodiesterase Inhibitors Is Independent of cGMP Signaling

Journal of Pharmacology and Experimental Therapeutics(2022)10.1124/jpet.121.001075Source: DataRank Database

Inhibition of Colon Cancer Cell Growth by Phosphodiesterase Inhibitors Is Independent of cGMP Signaling is a research paper published in Journal of Pharmacology and Experimental Therapeutics (2022). On theSindex it has a DataRank of 0. It has been cited 14 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access14 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (1 grants)Impact (FWCI 1.10)OA: bronzeTopics (36)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Alexis Wren,Namratha Mylarapu,Kaylin A. Browning,Bianca N. Islam ORCID,Rui Wang ORCID

Live enrichment

PubMed:35110391 PMC:PMC8998686 OpenAlex:https://openalex.org/W4210811131

NCI NIH HHS

Grant: R01 CA172627

FWCI

1.10

Citation Percentile

0.7%

Citation Trend

2022

2023

2024

2025

bronzeLicense: https://www.elsevier.com/legal/tdmrep-license

journalhttps://jpet.aspetjournals.org/content/jpet/381/1/42.full.pdf

BRONZEhttps://jpet.aspetjournals.org/content/jpet/381/1/42.full.pdf

publisherhttps://jpet.aspetjournals.org/content/jpet/381/1/42.full.pdf

publisherhttps://api.elsevier.com/content/article/PII:S0022356524002532?httpAccept=text/xml

publisherhttps://api.elsevier.com/content/article/PII:S0022356524002532?httpAccept=text/plain

Fields of Study

Phosphodiesterase function and regulationCoagulation, Bradykinin, Polyphosphates, and AngioedemaMast cells and histamineMedicineBiology

MeSH Terms

Cell Transformation, NeoplasticColonic NeoplasmsCyclic GMPHumansPhosphodiesterase InhibitorsPhosphoric Diester HydrolasesSignal TransductionCyclic GMP-Dependent Protein Kinases

Keywords

Cyclic guanosine monophosphatePhosphodiesteraseCell growthcGMP-dependent protein kinasePDE10AcGMP-specific phosphodiesterase type 5Signal transductionCancer researchProtein kinase ACancer cellKinaseChemistryCell biologyCancerBiologyEndocrinologyInternal medicineMedicineBiochemistryCyclin-dependent kinase 2Nitric oxideSildenafilEnzyme

Sustainable Development Goals

SDG 0: Good health and well-being