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Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain

Science Advances(2022)10.1126/sciadv.abm5563Source: DataRank Database

Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain is a research paper published in Science Advances (2022). On theSindex it has a DataRank of 0. It has been cited 61 times.

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Open Access61 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (18 grants)OA: goldTopics (16)IDs (PubMed, PMC)Annotations (2)

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Authors (15)

Rachel E. Woolley ORCID,T. Bertie Ansell ORCID,Eamon F.X. Byrne ORCID,Sara Frigui ORCID,Giovanni Luchetti ORCID

Live enrichment

PubMed:35658032 PMC:PMC9166294

European Research Council

Grant: 647278

Molecular analysis of the Hedgehog signal transduction complex in the primary cilium

Biotechnology and Biological Sciences Research Council

Grant: BB/R00126X/1

Nano to Meso and Back Again: Capturing and Exploiting Dynamic Heterogeneities in Biological Membranes via Large Scale Simulations

Wellcome Trust

Grant: 102164/Z/13/Z

Wellcome Trust

Grant: 203726/Z/16/Z

Wellcome Trust

Grant: 203141/Z/16/Z

NIGMS NIH HHS

Grant: R01 GM106078

NHLBI NIH HHS

Grant: R01 HL067773

Cancer Research UK

Grant: 26752

NIGMS NIH HHS

Grant: R35 GM118082

National Institutes of Health

Grant: 1F32GM013039-01

MOLECULAR ANALYSIS OF THE YEAST HEAT SHOCK TRANSCRIPTION

Wellcome Trust

Grant: 203141

Human Genetics and Disease Biology: Core Renewal for the Wellcome Trust Centre for Human Genetics

Wellcome Trust

Grant: 208361

LipID: A Lipid Annotation Tool for Membrane Proteins

Wellcome Trust

Grant: 203726

Oxford - Cellular Structural Biology

National Institutes of Health

Grant: 5R01HL067773-07

Mechanism of Endocytic Trafficking of Cholesterol

Wellcome Trust

Grant: 102164

Cellular Structural Biology

National Institutes of Health

Grant: 5R01GM106078-03

Signal Transduction by Oxysterols

National Institutes of Health

Grant: 5R35GM118082-04

Biochemical and cell biological mechanisms of signal transduction through the Hedgehog pathway

Wellcome Trust

goldLicense: http://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.abm5563

Europe_PMChttps://europepmc.org/articles/PMC9166294

Europe_PMChttps://europepmc.org/articles/PMC9166294?pdf=render

https://doi.org/10.1126/sciadv.abm5563

https://pubmed.ncbi.nlm.nih.gov/35658032

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

CysteineCholesterolSterolsLigandsHedgehog Proteins

Keywords

SterolsCholesterol572Medicine and Health SciencesHedgehog ProteinsBiomedicine and Life SciencesCysteineLigands