A genome scale transcriptional regulatory model of the human placenta is a dataset published in Science Advances (2024). On theSindex it has a DataRank of 0.489, placing it in the top 39.1% of the data-sharing corpus. It has been cited 18 times, with 11 citing works in its 1-hop citation network. Its calibrated FAIR score is 42/100.
Ranks in the top 39% for downstream scientific impact
Linked data & code
DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Full FAIR picture · advisory
The headline score is computed from the scored criteria — the fact-shaped checks (a repository, an accession, a licence) that two independent models agree on. The advisory criteria below are real FAIR guidance but rest on judgment calls that models read differently, so they inform without moving the number.
“The RNA-seq data from MWRI are available on GEO (GSE245395).”— not found in the paper; verdict downgraded
The sentence gives a GEO accession (GSE245395), which is a persistent identifier scheme accepted by the FAIR criteria. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
RDA-F1-01D — FAIR Data Maturity Model: 'Data is identified by a persistent identifier' (priorit · RDA-F1-02D — FAIR Data Maturity Model: 'Data is identified by a globally unique identifier' · FsF-F1-02D — F-UJI/FAIRsFAIR: 'Data is assigned a persistent identifier'
“The RNA-seq data from MWRI are available on GEO (GSE245395).”— not found in the paper; verdict downgraded
GEO is a named data repository, which is a class-1 holder. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
RDA-F4-01M — FAIR Data Maturity Model: metadata is offered so it can be harvested and indexed ( · NIH DMS Policy Element 4 (NOT-OD-21-014) — name the repository where data will be archived · NSTC Desirable Characteristics of Data Repositories (2022) — 'Long-Term Sustainability', 'Reten
“A. Paquette, Placental TRN Manuscript Code (2023), (available at 10.5281/zenodo.7741718).”— not found in the paper; verdict downgraded
The code dataset appears as a reference-list entry (reference 103) with a DOI, cited in the text as (103). [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
FORCE11 Joint Declaration of Data Citation Principles (2014) — data should be cited as a first- · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes · FsF-F3-01M — F-UJI: 'Metadata includes the identifier of the data it describes'
Advisory · not in the published score
“All data needed to evaluate the conclusions in the paper are present in the Supplementary Materials and in data repositories. Specifically, the code has been published in Zenodo (103). DNase-seq data are available from the ENCODE consortium (GEO IDs: GEO: GSE170432 , GEO: GSE170970 , GEO: GSE170355 , GEO: GSE170943 , GEO: GSE170767 , GEO: GSE170640 , GEO: GSE170752 , GEO: GSE170385 , GEO: GSE170238 , GEO: GSE170099 , GEO: GSE16979 , and GEO: GSE170978 ). The RNA-seq data from MWRI are available on GEO (GSE245395). RNA-seq data from the siRNA knockdown experiments are available on GEO (GSE245394). RNA-seq data for the CANDLE cohort are available on dbGAP (dbGAP ID phs003619.v1).”— not found in the paper; verdict downgraded
The data availability statement points to multiple repositories (Zenodo, GEO, dbGaP) with accessions, placing it in Colavizza category 3 (link to archived data in public repository). [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (3/5 passes agreed)]
Colavizza, Hrynaszkiewicz, Staden, Whitaker & McGillivray (2020), 'The citation advantage of li · Springer Nature research data policy — Data Availability Statements: standard statement templat · RDA-F3-01M — metadata clearly and explicitly includes the identifier of the data it describes
“Our final robust model contained 7712 genes, with a subset of this model including 3213 genes (41.7%) with OOS R2 prediction accuracy in our holdout dataset >0.5 (calculated from Lasso regression; Fig. 2B). Our final model was composed of 113,158 interactions between 391 TFs and 7712 target genes, including 75,014 positively correlated interactions and 38,144 negatively correlated interactions (Fig. 3A).”— not found in the paper; verdict downgraded
The dataset's content is described in running prose, not in an itemised inventory (section, table, or list). [downgraded to 'no' — no verifiable quote from the paper] [majority verdict 'no' (2/5 passes agreed)]
RDA-F2-01M — 'Rich metadata is provided to allow discovery' (priority Essential) · FsF-F2-01M — F-UJI: 'Metadata includes descriptive core elements to support data findability' · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data'
“The RNA-seq data from MWRI are available on GEO (GSE245395).”— not found in the paper; verdict downgraded
The sentence gives a route to the data (GEO) without stating any precondition, so the data are accessible without conditions. [downgraded to 'partial' — no verifiable quote from the paper] [majority verdict 'partial' (4/5 passes agreed)]
RDA-A1.1-01D — 'Data is accessible through a free access protocol' · FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · NSTC Desirable Characteristics of Data Repositories (2022) — 'Free and Easy Access'
Advisory · not in the published score
“Our final model contained 113,158 interactions across 391 TFs and 7712 target genes and is publicly available.”
The abstract explicitly labels the model as 'publicly available', which is a natural-language equivalent of an open access label. [majority verdict 'yes' (3/5 passes agreed)]
FsF-A1-01M — F-UJI: 'Metadata contains access level and access conditions of the data' · RDA-A1-01M — metadata contains information to enable the user to get access to the data · COAR Controlled Vocabularies — Access Rights v1.0 (open / embargoed / restricted / metadata-onl
“RNA-seq data for the CANDLE cohort are available on dbGAP (dbGAP ID phs003619.v1).”
dbGAP is a controlled-access repository with a Data Access Committee, serving as an institutional gatekeeper for sensitive human data. [majority verdict 'yes' (4/5 passes agreed)]
NIH Genomic Data Sharing Policy (NOT-OD-14-124) — controlled-access via a Data Access Committee · RDA-A1.2-01D — 'Data is accessible through an access protocol that supports authentication and · NIH DMS Policy Element 5 (NOT-OD-21-014) — Access, Distribution, or Reuse Considerations (conse
No sentence in the paper states when the data become available or how long they persist; only current availability is mentioned. [majority verdict 'no' (3/5 passes agreed)]
NIH DMS Plan Element 4 (NOT-OD-21-014) — Data Preservation, Access, and Associated Timelines · NSTC Desirable Characteristics (2022), Organizational Infrastructure: 'Retention Policy' · RDA-A2-01M — 'Metadata is guaranteed to remain available after data is no longer available'
No file format token is named for the released data.
FsF-R1.3-02D — F-UJI: 'Data is available in a file format recommended by the target research co · RDA-R1.3-02D — data is expressed in a machine-understandable community standard · RDA-I1-01D — data uses a knowledge representation expressed in a standardised format
Advisory · not in the published score
No data or metadata community standard (e.g., MIAME, MINSEQE, GO) is named in the paper.
RDA-R1.3-01M — 'Metadata complies with a community standard' (priority Essential) · RDA-R1.3-01D — 'Data complies with a community standard' · RDA-I2-01M — '(Meta)data use vocabularies that follow FAIR principles'
No identifier for an external resource (other than the study's own data) is given in the text.
RDA-I3-01M — '(meta)data include references to other (meta)data' · RDA-I3-03M — 'metadata includes qualified references to other metadata' · FsF-I3-01M — F-UJI: 'Metadata includes links between the data and its related entities'
No licence is named for the data; the CC BY-NC license applies only to the article. [majority verdict 'no' (4/5 passes agreed)]
RDA-R1.1-01M — 'Metadata includes information about the licence under which the data can be reu · RDA-R1.1-02M — 'Metadata refers to a standard reuse licence' · RDA-R1.1-03M — 'Metadata refers to a machine-understandable reuse licence'
No version token or date is provided to identify the exact snapshot of the data. [majority verdict 'no' (2/5 passes agreed)]
DataCite Metadata Schema 4.6 — the 'Version' property · RDA-R1.2-01M — provenance information (which version was used is provenance) · NSTC Desirable Characteristics of Data Repositories (2022) — 'Provenance', 'Retention Policy'
“All code is publicly available in the following github repository ( https://github.com/AlisonPaquette/PlacentalTRN_ManuscriptCode/ ).”
The paper gives a machine-resolvable code-forge URL for the study's own code. [majority verdict 'yes' (4/5 passes agreed)]
NIH DMS Policy Element 2 (NOT-OD-21-014) — 'Related Tools, Software and/or Code' · FAIR4RS Principles v1.0 (Chue Hong et al., 2022; RDA/FORCE11/ReSA) — FAIR Principles for Resear · FORCE11 Software Citation Principles (Smith, Katz & Niemeyer, 2016, PeerJ CS 2:e86)
“R01 HL109977”
The paper provides a specific grant number (R01 HL109977) attached to the National Heart, Lung, and Blood Institute.
DataCite Metadata Schema 4.6 — 'FundingReference' property (funderName, funderIdentifier, award · Crossref Funder Registry — canonical funder identifiers for funding metadata · RDA-F2-01M — rich metadata provided to allow discovery (funding is part of the descriptive reco
Advisory · not in the published score
“Transcript abundances were estimated using the quantification program Kallisto”
The paper names a specific software tool (Kallisto) used to produce the data, which is a proper-noun artefact. [majority verdict 'yes' (4/5 passes agreed)]
RDA-R1.2-01M — 'Metadata includes provenance information according to community- specific standa · FsF-R1.2-01M — F-UJI: 'Metadata includes provenance information about data creation or generati · W3C PROV-O (W3C Recommendation, 2013) — the entity/activity/agent model of provenance
“Table 1. Covariate data from cohorts used for RNA-seq and DNase-seq data.”
Variable definitions are provided inside the article (Table 1) rather than in a separate documentation object shipped with the data. [majority verdict 'partial' (3/5 passes agreed)]
RDA-R1-01M — '(Meta)data are richly described with a plurality of accurate and relevant attribu · FsF-R1-01MD — F-UJI: 'Metadata specifies the content of the data' · NIH DMS Policy Element 3 (NOT-OD-21-014) — Standards (documentation and metadata to accompany t
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.442
From this paper's citation signal
Citation Network Contribution
0.0472
From 5 citing papers with measurable signal
Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 11 citers.
NICHD NIH HHS
Grant: R00 HD096112
NIEHS NIH HHS
Grant: P30 ES007033
NIH HHS
Grant: UH3 OD023271
NICHD NIH HHS
Grant: R01 HD091527
NHLBI NIH HHS
Grant: R01 HL109977
NIH HHS
Grant: UG3 OD023271
NICHD NIH HHS
Grant: K99 HD096112
NIH HHS
Grant: UG3 OD035528
National Institutes of Health
Grant: 5R01HL109977-04
Pregnancy Folate Status & Early Childhood Respiratory & Atopic Disease Outcomes
National Institutes of Health
Grant: 4R00HD096112-03
The Role of Corticotrophin Releasing Hormone on Placental Transcriptional Networks and Birth Timing
National Institutes of Health
Grant: 5R01HD091527-04
Harnessing "omics": A Systems Biology approach to discovery of biological pathways in placental development and parturition
National Institutes of Health
Grant: 3P30ES007033-18S1
Center for Ecogenetics and Environmental Health
National Institutes of Health
Grant: 1UG3OD023271-01
Prenatal and Early Childhood Pathways To Health: An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory Outcomes
FWCI
3.36
Citation Percentile
0.9%
Citation Trend
Fields of Study
MeSH Terms
Keywords