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Caspase-2 is essential for proliferation and self-renewal of nucleophosmin-mutated acute myeloid leukemia

Science Advances(2024)10.1126/sciadv.adj3145Source: DataRank Database

Caspase-2 is essential for proliferation and self-renewal of nucleophosmin-mutated acute myeloid leukemia is a research paper published in Science Advances (2024). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Enrichment:Funding (14 grants)OA: goldTopics (32)IDs (PubMed, PMC)

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Authors (18)

Alexandra N. Brown-Suedel,Karla E. Rojas López ORCID,Suruchi Salgar ORCID,Luiza E. Coutinho,Francesca Keane

Live enrichment

PubMed:39093977 PMC:PMC11296348

NCI NIH HHS

Grant: R21 CA256606

NIDDK NIH HHS

Grant: T32 DK060445

NCI NIH HHS

Grant: P30 CA125123

NHLBI NIH HHS

Grant: T32 HL170967

NIH HHS

Grant: S10 OD028648

NIGMS NIH HHS

Grant: R01 GM121389

NIGMS NIH HHS

Grant: T32 GM136560

National Institutes of Health

Grant: 5T32GM136560-03

Training Program in Cell and Molecular Biology

National Institutes of Health

Grant: 1R21CA256606-01

Mechanisms of caspase-2 activation by nucleophosmin in AML cell death and survival

National Institutes of Health

Grant: 3P30CA125123-09S3

Baylor College of Medicine Cancer Center

National Institutes of Health

Grant: 1S10OD028648-01

Quanterix 2470 Arrayer for Reverse Phase Protein Array Technology

National Institutes of Health

Grant: 5R01GM121389-03

Non-apoptotic functions of caspase-2 in cell division and genomic stability

National Institutes of Health

Grant: 2T32DK060445-16

Hematology Training Program

National Institutes of Health

Grant: 1F32GM013039-01

MOLECULAR ANALYSIS OF THE YEAST HEAT SHOCK TRANSCRIPTION

goldLicense: http://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited.

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adj3145

Europe_PMChttps://europepmc.org/articles/PMC11296348

Europe_PMChttps://europepmc.org/articles/PMC11296348?pdf=render

https://doi.org/10.1126/sciadv.adj3145

https://pubmed.ncbi.nlm.nih.gov/39093977

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Cell Line, TumorAnimalsHumansMiceDNA DamageNuclear ProteinsApoptosisCell DifferentiationCell ProliferationMutationCaspase 2Leukemia, Myeloid, AcuteCell Self RenewalNucleophosmin

Keywords

Caspase 2Nuclear ProteinsApoptosisCell DifferentiationLeukemia, Myeloid, AcuteMiceCell Line, TumorMutationHumansAnimalsBiomedicine and Life SciencesCell Self RenewalNucleophosminCell ProliferationDNA Damage