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The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma

Science Advances(2024)10.1126/sciadv.adm9449Source: DataRank Database

The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN- amplified neuroblastoma is a research paper published in Science Advances (2024). On theSindex it has a DataRank of 0. It has been cited 19 times.

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Open Access19 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (14 grants)Impact (FWCI 5.30)OA: goldTopics (79)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Nathaniel W. Mabe ORCID,Alexandra B. Forman ORCID,Gabriela Alexe ORCID,Kathleen Engel ORCID,Ying-Jiun C. Chen ORCID

Live enrichment

PubMed:38820154 PMC:PMC11141635 OpenAlex:https://openalex.org/W4399205824

NCI NIH HHS

Grant: F32 CA261035

NCI NIH HHS

Grant: R00 CA279915

NCI NIH HHS

Grant: P01 CA217959

NCI NIH HHS

Grant: F32 CA243266

NCI NIH HHS

Grant: R35 CA283977

NCI NIH HHS

Grant: K99 CA279915

NIGMS NIH HHS

Grant: R35 GM131678

National Institutes of Health

Grant: 5F32CA243266-02

Elucidating the role of the SAGA complex in MYCN-amplified neuroblastoma

National Institutes of Health

Grant: 1F32GM013039-01

MOLECULAR ANALYSIS OF THE YEAST HEAT SHOCK TRANSCRIPTION

National Institutes of Health

Grant: 1R35GM131678-01

Genetic and Molecular Definition of Histone Modifying Enzyme Functions

National Institutes of Health

Grant: 1R35CA283977-01

Targeting Pediatric Cancer Vulnerabilities

National Institutes of Health

Grant: 1K99CA279915-01

Defining PRC1.1 as a gatekeeper of lineage plasticity and response to anti-GD2 therapy

National Institutes of Health

Grant: 7P01CA217959-04

Discovering and Exploiting Mechanisms of Neuroblastoma Therapy Resistance

National Institutes of Health

Grant: 3F32CA261035-01S1

Elucidating the Role of Epigenetic Plasticity in anti-GD2 Immunotherapy Response

FWCI

5.30

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttps://www.science.org/doi/pdf/10.1126/sciadv.adm9449?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adm9449?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adm9449

journalhttps://doi.org/10.1126/sciadv.adm9449

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38820154

Fields of Study

Neuroblastoma Research and TreatmentsProtein Degradation and InhibitorsUbiquitin and proteasome pathways0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsHumansMiceAcetylationCell Line, TumorChromatinGene AmplificationGene Expression Regulation, NeoplasticHistone AcetyltransferasesHistonesN-Myc Proto-Oncogene ProteinNeuroblastomaLysine AcetyltransferasesTrans-Activators

MeSH Terms

Lysine AcetyltransferasesN-Myc Proto-Oncogene ProteinAcetylationAnimalsChromatinGene AmplificationHistonesHumansNeuroblastomaTrans-ActivatorsGene Expression Regulation, NeoplasticCell Line, TumorMiceHistone Acetyltransferases

Keywords

NeuroblastomaBiologyHistoneHistone acetyltransferaseCoactivatorChromatinGeneCancer researchTranscription factorRegulation of gene expressionGene expressionPOU domainGeneticsCell cultureMedical SciencesBioinformatics610PediatricsCell LineBiomedical InformaticsHistonesMiceCell Line, TumorMedical SpecialtiesMedicine and Health Sciencesand ImmunityAnimalsHumansBiological PhenomenaHistone AcetyltransferasesNeoplasticN-Myc Proto-Oncogene ProteinTumorCell PhenomenaGene Amplification500AcetylationLysine AcetyltransferasesGene Expression Regulation, NeoplasticGene Expression RegulationOncologyMedical MicrobiologyMedical Molecular BiologyTrans-ActivatorsBiomedicine and Life Sciences

Sustainable Development Goals

SDG 0: Good health and well-being