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Small-molecule probe for IBD risk variant GPR65 I231L alters cytokine signaling networks through positive allosteric modulation

Science Advances(2024)10.1126/sciadv.adn2339Source: DataRank Database

Small-molecule probe for IBD risk variant GPR65 I231L alters cytokine signaling networks through positive allosteric modulation is a research paper published in Science Advances (2024). On theSindex it has a DataRank of 0. It has been cited 8 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access8 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 3.16)OA: goldTopics (37)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

C. Subba Reddy ORCID,Zher Yin Tan ORCID,Bihua Li,Partha P. Nag,Joshua Park ORCID

Live enrichment

PubMed:39028811 PMC:PMC11259170 OpenAlex:https://openalex.org/W4400810083

NIDDK NIH HHS

Grant: P30 DK043351

NIDDK NIH HHS

Grant: R01 DK117263

NIAID NIH HHS

Grant: U19 AI109725

National Institutes of Health

Grant: 5R01DK117263-04

Lysosome Homeostasis and Microbicidal Mechanisms in Innate Immunity

National Institutes of Health

Grant: 5U19AI109725-03

Autophagy Modulators as Novel Broad-Spectrum Anti-Infective Agents

FWCI

3.16

Citation Percentile

0.9%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttps://www.science.org/doi/pdf/10.1126/sciadv.adn2339?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adn2339?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adn2339

journalhttps://doi.org/10.1126/sciadv.adn2339

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39028811

Fields of Study

Inflammatory Bowel DiseaseHelicobacter pylori-related gastroenterology studiesGalectins and Cancer Biology0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

Allosteric RegulationAnimalsDendritic CellsHumansInflammatory Bowel DiseasesMolecular ProbesSignal TransductionCytokinesReceptors, G-Protein-CoupledMice

Keywords

Allosteric regulationModulation (music)CytokineSignal transductionChemistryCell biologyBiologyComputational biologyReceptorImmunologyBiochemistryPhysicsDendritic CellsInflammatory Bowel DiseasesReceptors, G-Protein-CoupledMiceMolecular ProbesHumansAnimalsCytokinesBiomedicine and Life Sciences

Sustainable Development Goals

SDG 0: Good health and well-being