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Generation of an inflammatory niche in a hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines

Science Advances(2025)10.1126/sciadv.adr2631Source: DataRank Database

Generation of an inflammatory niche in a hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines is a research paper published in Science Advances (2025). On theSindex it has a DataRank of 0. It has been cited 25 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access25 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (11 grants)Impact (FWCI 11.39)OA: goldTopics (64)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

John H. Klich ORCID,Carolyn K. Jons ORCID,Tianyang Mao ORCID,Namit Chaudhary ORCID,Ashley Utz ORCID

Live enrichment

PubMed:40215318 PMC:PMC11988412 OpenAlex:https://openalex.org/W4409357128

Gates Foundation

Grant: INV-010680

Gates Foundation

Grant: INV-027411

NIGMS NIH HHS

Grant: T32 GM008412

NIGMS NIH HHS

Grant: T32 GM145402

NIGMS NIH HHS

Grant: T32 GM007365

NIH HHS

Grant: S10 OD026831

National Institutes of Health

Grant: 1S10OD026831-01

30-parameter FACSymphony A3 flow cytometer for Shared Resource Lab

National Institutes of Health

Grant: 5T32GM008412-25

Graduate Training Program in Biotechnology

National Institutes of Health

Grant: 5T32GM007365-23

MEDICAL SCIENTIST TRAINING PROGRAM

National Institutes of Health

Grant: 5T32GM145402-04

Medical Scientist Training Program

National Institutes of Health

Grant: 1S10RR013039-01

MICROPLATE SCINTILLATION/LUMINESCENCE/FLOUR COUNTER

FWCI

11.39

Citation Percentile

1.0%

Influential Citations

Citation Trend

2025

2026

goldLicense: cc-by-nc

journalhttps://www.science.org/doi/pdf/10.1126/sciadv.adr2631?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adr2631?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adr2631

journalhttps://doi.org/10.1126/sciadv.adr2631

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40215318

Fields of Study

RNA Interference and Gene DeliveryImmunotherapy and Immune ResponsesSARS-CoV-2 and COVID-19 ResearchMedicineEngineeringHydrogelsAnimalsRNA, MessengerNanoparticlesMiceCOVID-19 VaccinesSARS-CoV-2COVID-19mRNA VaccinesHumansImmunity, HumoralAdjuvants, ImmunologicFemaleVaccines, SyntheticInflammationLiposomes

MeSH Terms

COVID-19SARS-CoV-2COVID-19 VaccinesmRNA VaccinesAdjuvants, ImmunologicAnimalsFemaleHumansInflammationLiposomesRNA, MessengerVaccines, SyntheticHydrogelsMiceNanoparticlesImmunity, Humoral

Keywords

Immune systemNicheMessenger RNAGerminal centerImmunologyBiologyCell biologyAntibodyB cellGeneInflammationVaccines, SyntheticCOVID-19 VaccinesSARS-CoV-2COVID-19HydrogelsImmunity, HumoralMiceAdjuvants, ImmunologicLiposomesAnimalsNanoparticlesHumansFemaleBiomedicine and Life SciencesRNA, MessengermRNA Vaccines

Sustainable Development Goals

SDG 0: Good health and well-being