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CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology

Science Advances(2025)10.1126/sciadv.adu0726Source: DataRank Database

CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology is a research paper published in Science Advances (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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Enrichment:Funding (19 grants)Impact (FWCI 2.32)OA: goldTopics (54)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (21)

Kohei Kano ORCID,Sadhna Phanse ORCID,Mai K. Nguyen ORCID,Elyssa B. Margolis ORCID,YuHong Fu ORCID

Live enrichment

PubMed:41237231 PMC:PMC12617525 OpenAlex:https://openalex.org/W4416222336

National Institutes of Health

Grant: R01 AG065428

National Institutes of Health

Grant: RF1 AG064170

National Institutes of Health

Grant: NIH RR18928

Michael J. Fox Foundation for Parkinson's Research

Grant: ASAP-020529

University of California, San Francisco

Grant: K12GM081266

Canadian Institutes of Health Research

Grant: FDN-154318

Canadian Institutes of Health Research

Grant: PJT-186258

NINDS NIH HHS

Grant: R35 NS122209

NCRR NIH HHS

Grant: C06 RR018928

Canadian Institutes of Health Research

Grant: unidentified

unidentified

Berkelhammer Award for Excellence in Neuroscience

Parkinson Canada

UCSF Nutrition Obesity Research Center

Canada Foundation for Innovation

Dr. and Mrs. C.Y. Soong Fellowship

Government Scholarship to Study Abroad by the Ministry of Education in Taiwan

Joan and David Traitel Family Trust

Betty Brown’s Family

UCSF Bakar Aging Research Institute

FWCI

2.32

Citation Percentile

0.9%

Citation Trend

2026

goldLicense: cc-by

journalhttps://doi.org/10.1126/sciadv.adu0726

publisherhttps://doi.org/10.1126/sciadv.adu0726

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adu0726

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41237231

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12617525

Fields of Study

Parkinson's Disease Mechanisms and TreatmentsMitochondrial Function and PathologyGenetic Neurodegenerative Diseases03 medical and health sciences0302 clinical medicineAnimalsMitochondriaParkinson DiseaseMicealpha-SynucleinReactive Oxygen SpeciesDisease Models, AnimalMitochondrial ProteinsMutationDopaminergic NeuronsTranscription FactorsHumansDNA-Binding ProteinsSubstantia Nigra

MeSH Terms

AnimalsDisease Models, AnimalDNA-Binding ProteinsHumansMitochondriaMutationParkinson DiseaseSubstantia NigraTranscription FactorsReactive Oxygen SpeciesMitochondrial ProteinsMicealpha-SynucleinDopaminergic Neurons

Keywords

MitochondrionSubstantia nigraPathophysiologyDopaminergicMutantMitochondrial DNAPhenotypeReactive oxygen speciesDopaminergic NeuronsParkinson DiseaseMitochondriaMitochondrial ProteinsDNA-Binding ProteinsMiceDisease Models, AnimalMutationalpha-SynucleinAnimalsHumansNeuroscienceTranscription Factors

CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology

FAIR Checklist

Authors (21)

Funding (19 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)