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A nut-and-bolt assembly of the bimodular large progenitor botulinum neurotoxin complex

Science Advances(2025)10.1126/sciadv.adx5831Source: DataRank Database

A nut-and-bolt assembly of the bimodular large progenitor botulinum neurotoxin complex is a research paper published in Science Advances (2025). On theSindex it has a DataRank of 0. It has been cited 2 times.

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Open Access2 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (13 grants)Impact (FWCI 1.71)OA: goldTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Linfeng Gao ORCID,Adina Przykopanski,Baohua Chen ORCID,Ting Huang ORCID,Maren Krüger ORCID

Live enrichment

PubMed:40864694 PMC:PMC12383247 OpenAlex:https://openalex.org/W4413756113

NIAID NIH HHS

Grant: R01 AI125704

NIGMS NIH HHS

Grant: P30 GM124165

NIAID NIH HHS

Grant: R01 AI158503

NIH HHS

Grant: S10 OD021527

NIAID NIH HHS

Grant: R01 AI173059

NIGMS NIH HHS

Grant: R01 GM151334

National Institutes of Health

Grant: 3P30GM124165-03S1

NE-CAT: A Resource for Advanced Macromolecular Crystallography

National Institutes of Health

Grant: 5R01AI158503-03

Developing broad-spectrum therapeutics against C. difficile toxins

National Institutes of Health

Grant: 1R01AI125704-01

Molecular mechanisms of botulinum neurotoxin neutralization

National Institutes of Health

Grant: 5R01AI173059-02

A versatile structure-based therapeutic platform for development of VHH-based antitoxin and antiviral agents

National Institutes of Health

Grant: 1F32GM013039-01

MOLECULAR ANALYSIS OF THE YEAST HEAT SHOCK TRANSCRIPTION

National Institutes of Health

Grant: 5R01GM151334-03

Resolving the intoxication mechanism of botulinum neurotoxins using single molecule structural biology

National Institutes of Health

Grant: 1S10OD021527-01

Pixel Array Detector for Macromolecular Crystallography

FWCI

1.71

Citation Percentile

0.9%

Influential Citations

Citation Trend

2026

goldLicense: cc-by-nc

journalhttps://www.science.org/doi/pdf/10.1126/sciadv.adx5831?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adx5831?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adx5831

journalhttps://doi.org/10.1126/sciadv.adx5831

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40864694

Fields of Study

Botulinum Toxin and Related Neurological DisordersNeurological disorders and treatmentsConnective tissue disorders researchMedicineBiology0301 basic medicine03 medical and health sciencesCrystallography, X-RayBotulinum Toxins, Type AModels, MolecularProtein BindingProtein MultimerizationNeurotoxinsProtein ConformationBacterial ProteinsAmino Acid Sequence

MeSH Terms

Amino Acid SequenceBacterial ProteinsModels, MolecularNeurotoxinsProtein BindingProtein ConformationCrystallography, X-RayBotulinum Toxins, Type AProtein Multimerization

Keywords

ProgenitorBotulinum neurotoxinNeurotoxinProgenitor cellNutComputer scienceChemistryBiologyEngineeringCell biologyStructural engineeringBiochemistryStem cellModels, MolecularBacterial ProteinsProtein ConformationNeurotoxinsBiomedicine and Life SciencesAmino Acid SequenceBotulinum Toxins, Type AProtein MultimerizationCrystallography, X-RayProtein Binding