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The tumor suppressor LACTB remodels mitochondria to promote cytochrome c release and apoptosis

Science Advances(2025)10.1126/sciadv.adx7809Source: DataRank Database

The tumor suppressor LACTB remodels mitochondria to promote cytochrome c release and apoptosis is a research paper published in Science Advances (2025). On theSindex it has a DataRank of 0. It has been cited 4 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access4 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 1.95)OA: goldTopics (30)IDs (PubMed, PMC, OpenAlex)Annotations (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Taewook Kang ORCID,Radu V. Stan ORCID,Edward J. Usherwood ORCID,Henry N. Higgs ORCID,Sukrut C. Kamerkar ORCID

Live enrichment

PubMed:41223265 PMC:PMC12609066 OpenAlex:https://openalex.org/W4416203161

National Institutes of Health

Grant: R35 GM122545

National Institutes of Health

Grant: R01 DK088826

National Institutes of Health

Grant: R01 CA257954

National Institutes of Health

Grant: R01 HL155824

National Institutes of Health

Grant: P20 GM113132

Dartmouth College

Grant: 5P30CA023108

Dartmouth College

Grant: 025077

NCI NIH HHS

Grant: P30 CA023108

FWCI

1.95

Citation Percentile

0.9%

Citation Trend

2026

goldLicense: cc-by

journalhttps://www.science.org/doi/pdf/10.1126/sciadv.adx7809?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adx7809?download=true

publisherhttps://www.science.org/doi/pdf/10.1126/sciadv.adx7809

journalhttps://doi.org/10.1126/sciadv.adx7809

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41223265

Fields of Study

Cell death mechanisms and regulationMitochondrial Function and PathologyCancer Research and TreatmentsApoptosisHumansMitochondriaCytochromes cMitochondrial MembranesTumor Suppressor Proteinsbcl-2-Associated X ProteinHeLa Cells

MeSH Terms

HeLa CellsHumansMitochondriaApoptosisTumor Suppressor ProteinsCytochromes cbcl-2-Associated X ProteinMitochondrial MembranesHela Cells

Keywords

Cytochrome cMitochondrionApoptosisMitochondrial apoptosis-induced channelMediatorInner mitochondrial membraneGene knockdownRegulatorProgrammed cell deathIntrinsic apoptosis

The tumor suppressor LACTB remodels mitochondria to promote cytochrome c release and apoptosis

FAIR Checklist

Authors (5)

Funding (8 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)