Complement: Increased Efficiency of the Second Component after Treatment with Iodoacetamide is a research paper published in Science (1965). On theSindex it has a DataRank of 0.396. It has been cited 5 times, with 3 citing works in its 1-hop citation network. Its calibrated FAIR score is 43/100.
The apparent activity of the second component of human complement was enhanced by treatment of the purified protein with iodoacetamide. By contrast, treatment with iodoacetic acid or p -chloromercuribenzoate led to inactivation. Treatment with iodoacetamide prevented the effect of p -chloromercuribenzoate and vice versa. Enhanced activity was partly due to increased stability of the otherwise labile intermediate complex consisting of erythrocytes, antibody, and the first, second, and fourth components of complement.
FAIR checklist signals are shown for context only and do not affect DataRank scoring.
Calibrated FAIR score — a parallel quality metric, independent of the DataRank citation score. See the full evaluation →
Base Score Contribution
0.269
From this paper's citation signal
Citation Network Contribution
0.127
From 2 citing papers with measurable signal
DataRank blends this paper's own citation count with the influence of the papers that cite it. Here, roughly 68% comes from its base citations and 32% from the citation network (2 citing papers contributed measurable signal).
Citers are pulled from OpenAlex sorted by cited_by_count:descand capped per paper, so when the cap binds we keep the highest-signal references and the score is reproducible across reruns.
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