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HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation

Science(2020)10.1126/science.aas8995Source: DataRank Database

HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation is a research paper published in Science (2020). On theSindex it has a DataRank of 0. It has been cited 387 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access387 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (7 grants)Impact (FWCI 15.95)OA: greenTopics (70)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (19)

Roberto Negro ORCID,Yuzi Tian ORCID,Arthur V. Hauenstein ORCID,Giuseppe Di Caprio ORCID,Wesley Skillern ORCID

Live enrichment

PubMed:32943500 PMC:PMC7814939 OpenAlex:https://openalex.org/W3087139986

National Institutes of Health

Grant: Al124491

NIGMS NIH HHS

Grant: R35 GM130386

NIAID NIH HHS

Grant: R01 AI124491

NICHD NIH HHS

Grant: DP1 HD087988

National Institutes of Health

Grant: 5DP1HD087988-05

SMOCs: Novel Signal Transduction Complexes as New Targets for Drug Discovery

National Institutes of Health

Grant: 5R35GM130386-02

VISUALIZATION OF SUBCELLULAR DYNAMICS IN MULTICELLULAR ORGANISMS

National Institutes of Health

Grant: 5R01AI124491-08

NLRP1 and CARD8 Inflammasomes: Assembly, Regulation and Stress Sensing

FWCI

15.95

Citation Percentile

1.0%

Citation Trend

2020

2021

2022

2023

2024

2025

2026

green

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7814939

publisherhttps://syndication.highwire.org/content/doi/10.1126/science.aas8995

publisherhttps://www.science.org/doi/pdf/10.1126/science.aas8995

journalhttps://doi.org/10.1126/science.aas8995

Fields of Study

Inflammasome and immune disordersAdenosine and Purinergic Signalinginterferon and immune responses0301 basic medicine03 medical and health sciencesAnimalsDNA-Binding ProteinsHEK293 CellsHistone Deacetylase 6HumansImmunologic SurveillanceInflammasomesLipopolysaccharidesMacrophagesMiceMice, Inbred C57BLMice, Mutant StrainsMicrotubule-Organizing CenterMicrotubulesNLR Family, Pyrin Domain-Containing 3 ProteinProtein TransportPyrin

MeSH Terms

PyrinNLR Family, Pyrin Domain-Containing 3 ProteinHistone Deacetylase 6AnimalsDNA-Binding ProteinsHumansImmunologic SurveillanceLipopolysaccharidesMacrophagesMice, Inbred C57BLMice, Mutant StrainsMicrotubulesProtein TransportMicrotubule-Organizing CenterMiceHEK293 CellsInflammasomes

Keywords

AggresomeInflammasomePyrin domainHDAC6Mechanism (biology)ChemistryCell biologyBiologyImmunologyGeneticsUbiquitinInflammationPhysicsGeneLipopolysaccharidesInflammasomesMacrophagesPyrinHistone Deacetylase 6MicrotubulesMice, Mutant StrainsDNA-Binding ProteinsMice, Inbred C57BLMiceProtein TransportHEK293 CellsNLR Family, Pyrin Domain-Containing 3 ProteinAnimalsHumansImmunologic SurveillanceMicrotubule-Organizing Center

Sustainable Development Goals

SDG 0: Good health and well-being