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T cell circuits that sense antigen density with an ultrasensitive threshold

Science(2021)10.1126/science.abc1855Source: DataRank Database

T cell circuits that sense antigen density with an ultrasensitive threshold is a research paper published in Science (2021). On theSindex it has a DataRank of 0. It has been cited 186 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access186 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)OA: bronzeTopics (47)IDs (PubMed)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (11)

Wei Yu ORCID,Katelyn A. Cabral ORCID,Olivia A. Creasey ORCID,Maria del Pilar Lopez Pazmino ORCID,Yurie Tonai ORCID

Live enrichment

PubMed:33632893

National Institutes of Health

Grant: 3P50GM081879-05S1

Exploring Design Principles of Cellular Control Circuits

National Institutes of Health

Grant: 5R01CA196277-05

Redesigning the T cell: Using Synthetic Biology to Engineer Therapeutic Cells

National Institutes of Health

Grant: 3U54CA244438-01S5

UCSF Center for Synthetic Immunology: Tools to Reprogram the Immune System to Combat Cancer

bronzeLicense: https://www.biorxiv.org/about/FAQ#license

https://doi.org/10.1101/2021.01.21.427654

https://helda.helsinki.fi/bitstream/10138/330717/1/1166.full.pdf

https://doi.org/10.1126/science.abc1855

https://pubmed.ncbi.nlm.nih.gov/33632893

https://dx.doi.org/10.1126/science.abc1855

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

Keywords

NotchCytotoxicGeneral Science & TechnologyT-LymphocytesOncology and CarcinogenesisImmunologyAdoptive610Immunotherapy, AdoptiveErb-b2 Receptor Tyrosine KinasesCell LineMiceErbB-2Antigens, NeoplasmCell Line, TumorSpheroids, CellularReceptorsGenetics2.1 Biological and endogenous factorsAnimalsHumansAntigensCell EngineeringCancerTumorReceptors, Chimeric AntigenBiomedical and Clinical Sciences5.2 Cellular and gene therapiesReceptors, NotchChimeric AntigenReceptors, ArtificialGene TherapyXenograft Model Antitumor Assays620ArtificialWomen's HealthNeoplasmImmunotherapyCellularSpheroidsK562 CellsBiotechnologyReceptorT-Lymphocytes, Cytotoxic

Sustainable Development Goals

SDG 3: 3. Good health