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Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody

Science(2021)10.1126/science.abf4830Source: DataRank Database

Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody is a research paper published in Science (2021). On theSindex it has a DataRank of 0. It has been cited 392 times.

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Open Access392 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (21 grants)OA: hybridTopics (50)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (27)

Longping V. Tse ORCID,Chengzi I. Kaku ORCID,Daniel Wrapp ORCID,Mrunal Sakharkar ORCID,Deli Huang ORCID

Live enrichment

PubMed:33495307 PMC:PMC7963221

National Institutes of Health

Grant: R01-AI12751

National Institutes of Health

Grant: R01-AI132317

National Institutes of Health

Grant: R01-AI073148

National Institutes of Health

Grant: RO1-AI132178

National Institutes of Health

Grant: U54 CA260543

National Institutes of Health

Grant: 5U19AI142777

Bill and Melinda Gates Foundation

Grant: OPP 1183956

NIAID NIH HHS

Grant: R01 AI157155

NIAID NIH HHS

Grant: R01 AI127521

NIAID NIH HHS

Grant: R01 AI132317

NIAID NIH HHS

Grant: R01 AI073148

NIAID NIH HHS

Grant: U19 AI142777

NCI NIH HHS

Grant: P30 CA008748

NIAID NIH HHS

Grant: R01 AI132178

National Institutes of Health

Grant: 5R01AI073148-13

Knock-in mice expressing germline-reverted broadly neutralizing HIV antibodies

National Institutes of Health

Grant: 4U54CA260543-02

North Carolina Seronet Center for Excellence

National Institutes of Health

Grant: 5U19AI142777-04

Prometheus: A Platform for Rapid Development of Human Antibody-based Therapeutics and Prophylactics against Emerging Viral Threats

National Institutes of Health

Grant: 1R01AG012751-01

PENSION AND SOCIAL SECURITY WEALTH IN THE HRS

National Institutes of Health

Grant: 5R01AI132178-05

Broad-spectrum antiviral GS-5734 to treat MERS-CoV and related emerging CoV

National Institutes of Health

Grant: 5R01LM013039-02

HealthyMe/MiSalud Smartphone Application: Identifying Mechanisms to Engage African Americans and Hispanics in Personal Health Libraries

National Institutes of Health

Grant: 5R01AI132317-02

Germline targeting influenza immunogens

hybridLicense: cc-by

publisherhttps://www.science.org/cms/asset/11268ce8-e1ae-423f-a1d5-4420b3bce627/pap.pdf

publisherhttps://syndication.highwire.org/content/doi/10.1126/science.abf4830

publisherhttps://www.science.org/doi/pdf/10.1126/science.abf4830

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7963221

repositoryhttps://doi.org/10.21430/m3wrg2rj32

Fields of Study

0301 basic medicine03 medical and health sciences

MeSH Terms

AnimalsMice, Inbred BALB CHumansMiceSevere Acute Respiratory SyndromeAntibodies, MonoclonalAntibodies, ViralBinding Sites, AntibodyEpitopesImmunization, PassiveDirected Molecular EvolutionProtein EngineeringAntibody AffinityBinding SitesImmunoglobulin Fc FragmentsCell Surface Display TechniquesSpike Glycoprotein, CoronavirusProtein DomainsBetacoronavirusBroadly Neutralizing AntibodiesCOVID-19Angiotensin-Converting Enzyme 2SARS-CoV-2Receptors, CoronavirusCOVID-19 SerotherapySevere acute respiratory syndrome-related coronavirus

Keywords

Mice, Inbred BALB CMultidisciplinaryBinding SitesAntibody AffinityImmunization, PassiveAntibodies, MonoclonalCOVID-19Antibodies, ViralProtein EngineeringImmunoglobulin Fc FragmentsBetacoronavirusEpitopesProtein DomainsAnimalsHumansAngiotensin-Converting Enzyme 2Binding Sites, AntibodyDirected Molecular EvolutionCell Surface Display TechniquesResearch ArticlesBroadly Neutralizing AntibodiesReceptors, Coronavirus

Sustainable Development Goals

SDG 3: 3. Good health