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Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production

Science(2022)10.1126/science.abg3067Source: DataRank Database

Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production is a research paper published in Science (2022). On theSindex it has a DataRank of 0. It has been cited 229 times.

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Scored on demand from live citation data

Open Access229 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (22 grants)Impact (FWCI 24.52)OA: greenTopics (69)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (29)

Kouji Kobiyama ORCID,Holger Winkels ORCID,Yanal Ghosheh ORCID,Sara McArdle ORCID,Zbigniew Mikulski ORCID

Live enrichment

PubMed:35025664 PMC:PMC9744443 OpenAlex:https://openalex.org/W4206622785

NHLBI NIH HHS

Grant: P01 HL136275

NHLBI NIH HHS

Grant: R01 HL126827

NIH HHS

Grant: S10 OD021831

NCRR NIH HHS

Grant: S10 RR027366

NIDDK NIH HHS

Grant: P30 DK120515

NHLBI NIH HHS

Grant: R01 HL145454

NHLBI NIH HHS

Grant: R01 HL103866

American Heart Association-American Stroke Association

Grant: 18CDA34110426

NHLBI NIH HHS

Grant: P01 HL088093

NHLBI NIH HHS

Grant: R01 HL115232

NHLBI NIH HHS

Grant: R01 HL130819

American Heart Association-American Stroke Association

Grant: 18POST34060251

NIDDK NIH HHS

Grant: R01 DK106000

NHLBI NIH HHS

Grant: R35 HL145241

National Institutes of Health

Grant: 1S10OD021831-01A1

Super-resolution confocal microscope

National Institutes of Health

Grant: 5P30DK120515-04

San Diego Digestive Diseases Research Center

National Institutes of Health

Grant: 5R01HL126827-02

Diet, Gut Microbiota, and Heart Failure

National Institutes of Health

Grant: 5R01HL103866-03

Gut flora metabolism of dietary phosphatidylcholine and cardiovascular disease

National Institutes of Health

Grant: 2R01HL115232-06

Myeloid cell interactions in atherosclerosis

National Institutes of Health

Grant: 5R01HL130819-03

Microbial Trimethylamine Lyases and Atherosclerosis

National Institutes of Health

Grant: 3P01HL088093-04S1

Program Project: Role of Innate Immunity in Atherosclerosis

National Institutes of Health

Grant: 5R01DK106000-03

Dietary Choline, Gut Microbiota, and Susceptibility for Chronic Kidney Disease

FWCI

24.52

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

green

repositoryhttps://escholarship.org/content/qt13f7j9d3/qt13f7j9d3.pdf

publisherhttps://www.science.org/doi/pdf/10.1126/science.abg3067

repositoryhttps://escholarship.org/uc/item/13f7j9d3

journalhttps://doi.org/10.1126/science.abg3067

Fields of Study

Olfactory and Sensory Function StudiesBiochemical Analysis and Sensing TechniquesNeuroinflammation and Neurodegeneration Mechanisms0301 basic medicine03 medical and health sciences

MeSH Terms

NLR Family, Pyrin Domain-Containing 3 ProteinAdultAldehydesAnimalsAortaHumansInterleukin-1MacrophagesMice, Inbred C57BLMiddle AgedLipid PeroxidationSignal TransductionReceptors, OdorantOxidative StressAtherosclerosisMiceInterleukin-1alphaInterleukin-1betaInflammasomes

Keywords

PathogenesisReceptorSniffingOctanalOlfactory systemImmunologyBiologyNeuroscienceChemistryBiochemistryAdultAgingGeneral Science & TechnologyInflammasomesInterleukin-1beta610NLR FamilyCardiovascularInbred C57BLReceptors, OdorantMiceInterleukin-1alpha616ReceptorsNLR Family, Pyrin Domain-Containing 3 Protein2.1 Biological and endogenous factorsAnimalsHumansAortaAldehydesBiomedical and Clinical SciencesMacrophagesNeurosciencesBiological SciencesMiddle AgedAtherosclerosisPyrin Domain-Containing 3 ProteinMice, Inbred C57BLOxidative StressOdorant5.1 PharmaceuticalsBiochemistry and Cell BiologyLipid PeroxidationInterleukin-1Signal Transduction