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Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies

Science(2022)10.1126/science.abl6502Source: DataRank Database

Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies is a research paper published in Science (2022). On theSindex it has a DataRank of 0. It has been cited 64 times.

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Open Access64 citations

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Enrichment:Funding (4 grants)Impact (FWCI 5.51)OA: greenTopics (70)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Jan Hellert ORCID,Natália Freitas ORCID,Pablo Guardado‐Calvo ORCID,Ahmed Haouz ORCID,J. Maximilian Fels ORCID

Live enrichment

PubMed:34793197 PMC:PMC9771711 OpenAlex:https://openalex.org/W3214301032

NIAID NIH HHS

Grant: U19 AI142777

National Institutes of Health

Grant: 5U19AI142777-04

Prometheus: A Platform for Rapid Development of Human Antibody-based Therapeutics and Prophylactics against Emerging Viral Threats

French National Research Agency (ANR)

Grant: ANR-11-LABX-0048

French National Research Agency (ANR)

Grant: ANR-11-IDEX-0007

FWCI

5.51

Citation Percentile

1.0%

Citation Trend

2022

2023

2024

2025

2026

greenLicense: cc-by

repositoryhttps://pasteur.hal.science/pasteur-03525373

publisherhttps://www.science.org/doi/pdf/10.1126/science.abl6502

journalhttps://doi.org/10.1126/science.abl6502

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34793197

Fields of Study

Viral Infections and VectorsVector-Borne Animal DiseasesVector-borne infectious diseases0301 basic medicine0303 health sciences03 medical and health sciencesAntibodies, NeutralizingAntibodies, ViralCrystallography, X-RayEpitopesHemorrhagic Fever Virus, Crimean-CongoHumansImmunoglobulin Fab FragmentsModels, MolecularNeutralization TestsProtein BindingProtein ConformationProtein DomainsProtein FoldingProtein MultimerizationViral Fusion ProteinsVirus Internalization

MeSH Terms

Protein DomainsAntibodies, ViralEpitopesHemorrhagic Fever Virus, Crimean-CongoHumansImmunoglobulin Fab FragmentsModels, MolecularNeutralization TestsProtein BindingProtein ConformationViral Fusion ProteinsProtein FoldingCrystallography, X-RayVirus InternalizationProtein MultimerizationAntibodies, Neutralizing

Keywords

VirologyAntibodyCrimean–Congo hemorrhagic feverVirusNeutralizationGlycoproteinTickLipid bilayer fusionBiologyAntigenImmunologyMolecular biologyModels, Molecular570Protein FoldingProtein Conformation[SDV]Life Sciences [q-bio]610Virus InternalizationAntibodies, ViralCrystallography, X-RayAntibodies, Neutralizing[SDV] Life Sciences [q-bio]EpitopesImmunoglobulin Fab FragmentsProtein DomainsNeutralization TestsHemorrhagic Fever Virus, Crimean-CongoHumansProtein MultimerizationViral Fusion ProteinsProtein Binding

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being

Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies

FAIR Checklist

Authors (14)

Funding (4 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)