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De novo design of drug-binding proteins with predictable binding energy and specificity

Science(2024)10.1126/science.adl5364Source: DataRank Database

De novo design of drug-binding proteins with predictable binding energy and specificity is a research paper published in Science (2024). On theSindex it has a DataRank of 0. It has been cited 69 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access69 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 11.29)OA: greenTopics (31)IDs (PubMed, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Xuxu Gou ORCID,Sophia K. Tan ORCID,Samuel I. Mann ORCID,Hyunjun Yang ORCID,Xiaofang Zhong ORCID

Live enrichment

PubMed:38574125 OpenAlex:https://openalex.org/W4393928505

NIA NIH HHS

Grant: P01 AG002132

NIGMS NIH HHS

Grant: P30 GM124169

NIGMS NIH HHS

Grant: T32 GM149436

NIGMS NIH HHS

Grant: R00 GM135519

NIAID NIH HHS

Grant: U19 AI171110

NIGMS NIH HHS

Grant: R35 GM122603

NHLBI NIH HHS

Grant: P01 HL146373

FWCI

11.29

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

greenLicense: cc-by

repositoryhttps://escholarship.org/content/qt1n36t5kk/qt1n36t5kk.pdf

publisherhttps://www.science.org/doi/pdf/10.1126/science.adl5364

repositoryhttps://escholarship.org/uc/item/1n36t5kk

journalhttps://doi.org/10.1126/science.adl5364

Fields of Study

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies ResearchComputational Drug Discovery MethodsHumansBinding SitesLigandsMolecular Dynamics SimulationPoly(ADP-ribose) Polymerase InhibitorsProtein BindingProteinsProtein EngineeringPharmacophore

MeSH Terms

Poly(ADP-ribose) Polymerase InhibitorsPharmacophoreBinding SitesCarrier ProteinsHumansLigandsProtein BindingProteinsDrug DesignProtein EngineeringPhysical PhenomenaMolecular Dynamics Simulation

Keywords

DrugChemistryPlasma protein bindingComputational biologyBiochemistryBiologyPharmacology

Sustainable Development Goals

SDG 0: Affordable and clean energy