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Brainwide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor

Science(2024)10.1126/science.ado7082Source: DataRank Database

Brainwide silencing of prion protein by AAV-mediated delivery of an engineered compact epigenetic editor is a research paper published in Science (2024). On theSindex it has a DataRank of 0. It has been cited 106 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access106 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 17.41)OA: hybridTopics (43)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (18)

Tessa M. Bertozzi ORCID,Elaine Wu,Fiona E. Serack ORCID,John W. Harvey ORCID,Pamela P. Brauer

Live enrichment

PubMed:38935715 PMC:PMC11875203 OpenAlex:https://openalex.org/W4400079395

NHGRI NIH HHS

Grant: RM1 HG009490

NIBIB NIH HHS

Grant: R01 EB029483

NINDS NIH HHS

Grant: UH3 NS111689

NIMH NIH HHS

Grant: UG3 MH120096

NINDS NIH HHS

Grant: U19 NS132315

Howard Hughes Medical Institute

FWCI

17.41

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

hybridLicense: cc-by

journalhttps://doi.org/10.1126/science.ado7082

publisherhttps://doi.org/10.1126/science.ado7082

publisherhttps://www.science.org/doi/pdf/10.1126/science.ado7082

repositoryhttps://pubmed.ncbi.nlm.nih.gov/38935715

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11875203

Fields of Study

CRISPR and Genetic EngineeringPrion Diseases and Protein MisfoldingHIV Research and TreatmentAnimalsHumansMiceBrainDependovirusDNA (Cytosine-5-)-MethyltransferasesDNA MethylationGene SilencingHistonesPrion DiseasesPrion ProteinsTransgenes

MeSH Terms

Prion ProteinsDependovirusAnimalsBrainDNA (Cytosine-5-)-MethyltransferasesHistonesHumansPrion DiseasesTransgenesDNA MethylationGene SilencingEpigenesis, GeneticMice

Keywords

EpigeneticsGene silencingHistoneBiologyCell biologyMethyltransferaseEndogenyTransgeneDNA methylationDNAMethylationGeneticsGene expressionBiochemistryGene

Sustainable Development Goals

SDG 0: Good health and well-being