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The essential genome of Plasmodium knowlesi reveals determinants of antimalarial susceptibility

Science(2025)10.1126/science.adq6241Source: DataRank Database

The essential genome of Plasmodium knowlesi reveals determinants of antimalarial susceptibility is a research paper published in Science (2025). On theSindex it has a DataRank of 0.543. It has been cited 25 times, with 22 citing works in its 1-hop citation network.

N/A

0.543DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access25 citations · 22 citing works in its network

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Linked data & code

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Data availability

Repositories this paper deposited data in (declared in PubMed).

SRAPRJNA1116591

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (3 grants)Impact (FWCI 26.96)OA: greenTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 90%Citation Network 10%

Base Score Contribution

0.489

From this paper's citation signal

Citation Network Contribution

0.0545

From 7 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 22 citers.

Validated Antimalarial Drug Target Discovery using Genome-Scale Metabolic Modelling
bioRxiv (Cold Spring Harbor Laboratory)20251 citations53 referencesContributes 0.013
The apicoplast transportome of the malaria parasite
Trends in Parasitology20252 citations107 referencesContributes 0.010
Genetic analysis of pyrimidine biosynthetic enzymes in Plasmodium falciparum
PLoS Pathogens20261 citations75 referencesContributes 0.009
PfATP2 is a flippase on the Plasmodium falciparum surface that is important for growth and influences parasite sensitivity to antiplasmodial compounds
PLoS Pathogens20251 citations81 referencesContributes 0.009
Characterisation of Two Plasmodium Virulence Factors Important for Lipid Metabolism and Disease Progression In Vivo
bioRxiv (Cold Spring Harbor Laboratory)20251 citations84 referencesContributes 0.008

Authors (13)

Sida Ye ORCID,Sheena Dass ORCID,Jacob A. Tennessen ORCID,Qudseen Sultana,Basil T. Thommen ORCID

Live enrichment

PubMed:39913579 PMC:PMC12104972 OpenAlex:https://openalex.org/W4407199653

NIAID NIH HHS

Grant: R01 AI168163

NIH HHS

Grant: P51 OD011132

NIAID NIH HHS

Grant: R01 AI167570

FWCI

26.96

Citation Percentile

1.0%

Citation Trend

2025

2026

green

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12104972/

publisherhttps://www.science.org/doi/pdf/10.1126/science.adq6241

journalhttps://doi.org/10.1126/science.adq6241

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39913579

Fields of Study

Malaria Research and ControlAquaculture disease management and microbiotavaccines and immunoinformatics approachesAnimalsHumansAntimalarialsArtemisininsDNA Transposable ElementsDrug ResistanceGenes, EssentialGenes, ProtozoanGenome, ProtozoanMalariaMitochondriaMutagenesis, InsertionalPlasmodium knowlesiGenetic Fitness

MeSH Terms

AnimalsAntimalarialsDNA Transposable ElementsDrug ResistanceHumansMalariaMitochondriaPlasmodium vivaxMutagenesis, InsertionalMutagenesisPlasmodium knowlesiGenes, ProtozoanGenome, ProtozoanGenes, EssentialArtemisininsGenetic Fitness

Keywords

Plasmodium knowlesiDruggabilityBiologyMalariaPlasmodium (life cycle)Plasmodium vivaxGenomePlasmodium falciparumDrug resistanceVirologyGeneticsComputational biologyGeneParasite hostingImmunology

Sustainable Development Goals

SDG 0: Good health and well-being

Related Papers (2)

Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy

N/A

0.464DataRank · unranked

bioRxiv (Cold Spring Harbor Laboratory)(2023)

co-cited

10.1101/2023.03.22.533773

Three-dimensional ultrastructure of Plasmodium falciparum throughout cytokinesis

Top 8%

2.9DataRank

PLoS Pathogens(2020)

co-cited

10.1371/journal.ppat.1008587

The essential genome of Plasmodium knowlesi reveals determinants of antimalarial susceptibility

FAIR Checklist

DataRank Breakdown

Top 5 citers driving the network score

Authors (13)

Funding (3 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)

Related Papers (2)