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Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding

Science Immunology(2020)10.1126/sciimmunol.abc2728Source: DataRank Database

Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding is a research paper published in Science Immunology (2020). On theSindex it has a DataRank of 0. It has been cited 86 times.

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Open Access86 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (11 grants)OA: greenTopics (66)IDs (PubMed, PMC)Annotations (1)SDGs (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (17)

Ashwin Somasundaram ORCID,Jessica Moskovitz ORCID,Andrea L. Szymczak-Workman ORCID,Chang Liu ORCID,Anthony R. Cillo ORCID

Live enrichment

PubMed:32680952 PMC:PMC7901539

NIH Office of the Director

Grant: P01 AI108545

NIH Office of the Director

Grant: R01 AI144422

NIH Office of the Director

Grant: EB022433

NIH Office of the Director

Grant: S10 OD011925-01

NCI NIH HHS

Grant: P30 CA047904

NIBIB NIH HHS

Grant: R01 EB022433

NIH HHS

Grant: S10 OD011925

NCI NIH HHS

Grant: P50 CA097190

National Institutes of Health

Grant: 5P01AI108545-08

Synergies among inhibitory receptors in tolerance, cancer & antiviral immunity

National Institutes of Health

Grant: 1S10OD011925-01

Special BD LSRFortessaTM

National Institutes of Health

Grant: 1R01AI144422-01

Structure, Function and Mechanistic Analysis of LAG3

greenLicense: CC BY NC SA

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/7901539

publisherhttps://syndication.highwire.org/content/doi/10.1126/sciimmunol.abc2728

publisherhttps://www.science.org/doi/pdf/10.1126/sciimmunol.abc2728

https://doi.org/10.1126/sciimmunol.abc2728

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7901539

Fields of Study

03 medical and health sciences0302 clinical medicineADAM10 ProteinAdenocarcinomaAnimalsAntigens, CDCell Line, TumorColonic NeoplasmsDrug Resistance, NeoplasmEncephalomyelitis, Autoimmune, ExperimentalFemaleHead and Neck NeoplasmsHumansImmune Checkpoint InhibitorsImmunotherapyMaleMelanoma, ExperimentalMice, TransgenicProgrammed Cell Death 1 ReceptorSkin NeoplasmsSquamous Cell Carcinoma of Head and NeckT-LymphocytesTranscriptomeLymphocyte Activation Gene 3 Protein

MeSH Terms

T-LymphocytesCell Line, TumorAnimalsMice, TransgenicHumansMelanoma, ExperimentalAdenocarcinomaColonic NeoplasmsHead and Neck NeoplasmsSkin NeoplasmsEncephalomyelitis, Autoimmune, ExperimentalAntigens, CDImmunotherapyDrug Resistance, NeoplasmFemaleMaleProgrammed Cell Death 1 ReceptorTranscriptomeADAM10 ProteinSquamous Cell Carcinoma of Head and NeckImmune Checkpoint InhibitorsLymphocyte Activation Gene 3 Protein

Keywords

MaleEncephalomyelitis, Autoimmune, ExperimentalSkin NeoplasmsSquamous Cell Carcinoma of Head and NeckT-LymphocytesProgrammed Cell Death 1 ReceptorMelanoma, ExperimentalMice, TransgenicAdenocarcinomaADAM10 ProteinAntigens, CDDrug Resistance, NeoplasmHead and Neck NeoplasmsCell Line, TumorColonic NeoplasmsAnimalsHumansFemaleImmunotherapyImmune Checkpoint Inhibitors

Sustainable Development Goals

SDG 3: 3. Good health

Resistance to PD1 blockade in the absence of metalloprotease-mediated LAG3 shedding

FAIR Checklist

Authors (17)

Funding (11 grants)

Open Access

Topics

Annotations (Europe PMC)