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A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression

Science Immunology(2024)10.1126/sciimmunol.adi4191Source: DataRank Database

A lactate-SREBP2 signaling axis drives tolerogenic dendritic cell maturation and promotes cancer progression is a research paper published in Science Immunology (2024). On theSindex it has a DataRank of 0.729. It has been cited 128 times.

N/A

0.729DataRank · unranked

Scored on demand from live citation data

Open Access128 citations

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Linked data & code

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 19.93)OA: greenTopics (51)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.729

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

This paper's DataRank is currently driven only by its base citation score. Citation network data was not refreshed for this result.

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Authors (9)

Yue Xue ORCID,Y‐Van Nguyen ORCID,Nicholas C. DeVito ORCID,X F Wang ORCID,Alisha Holtzhausen ORCID

Live enrichment

PubMed:38728412 PMC:PMC11926670 OpenAlex:https://openalex.org/W4396815136

NCI NIH HHS

Grant: P30 CA016086

NCI NIH HHS

Grant: R37 CA249085

NCI NIH HHS

Grant: F32 CA247067

NCI NIH HHS

Grant: P30 CA014236

NCI NIH HHS

Grant: R01 CA251136

FWCI

19.93

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

green

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11926670/pdf/nihms-2054584.pdf

publisherhttps://www.science.org/doi/pdf/10.1126/sciimmunol.adi4191

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11926670

journalhttps://doi.org/10.1126/sciimmunol.adi4191

Fields of Study

Immunotherapy and Immune ResponsesT-cell and B-cell ImmunologyImmune Cell Function and InteractionAnimalsFemaleHumansMiceCell Line, TumorDendritic CellsDisease ProgressionImmune ToleranceLactic AcidMelanomaMelanoma, ExperimentalMice, Inbred C57BLSignal TransductionSterol Regulatory Element Binding Protein 2Tumor Microenvironment

MeSH Terms

AnimalsDendritic CellsFemaleHumansImmune ToleranceMelanomaMelanoma, ExperimentalMice, Inbred C57BLSignal TransductionDisease ProgressionLactic AcidCell Line, TumorMiceSterol Regulatory Element Binding Protein 2Tumor Microenvironment

Keywords

Tumor microenvironmentBiologyCancer researchMelanomaDendritic cellFOXP3Immune systemCross-presentationCell biologyCancer immunotherapyGene silencingImmune toleranceTumor progressionT cellImmunotherapyImmunologyCancerAntigen presentation

Sustainable Development Goals

SDG 0: Good health and well-being