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Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2′- O -methyl transfer by SARS-CoV-2 nsp16

Science Signaling(2021)10.1126/scisignal.abh2071Source: DataRank Database

Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2′- O -methyl transfer by SARS-CoV-2 nsp16 is a research paper published in Science Signaling (2021). On theSindex it has a DataRank of 0. It has been cited 31 times.

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Enrichment:Funding (12 grants)OA: hybridTopics (44)IDs (PubMed, PMC)Annotations (4)SDGs (1)

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Authors (9)

Mónica Rosas‐Lemus ORCID,L. Shuvalova ORCID,Nicole L. Inniss ORCID,J.S. Brunzelle ORCID,Courtney M. Daczkowski ORCID

Live enrichment

PubMed:34131072 PMC:PMC8432954

National Cancer Institute

Grant: NCI CCSG P30 CA060553

National Cancer Institute

Grant: NCI R01-CA142861

National Institute of Allergy and Infectious Diseases

Grant: HHSN272201700060C

Argonne National Laboratory, Office of Science

Grant: DE-AC02-06CH11357

Chicago Biomedical Consortium

Grant: CR-003

Michigan Technology Tri Corridor

Grant: 085P1000817

NCI NIH HHS

Grant: R01 CA142861

NCI NIH HHS

Grant: P30 CA060553

NIH HHS

Grant: S10 OD023681

National Institutes of Health

Grant: 5R01LM013039-02

HealthyMe/MiSalud Smartphone Application: Identifying Mechanisms to Engage African Americans and Hispanics in Personal Health Libraries

National Institutes of Health

Grant: 5R01CA142861-02

HPV and the DNA Damage Response

National Institutes of Health

Grant: 5P30CA060553-12

The Robert H.Lurie Comprehensive Cancer Center

hybridLicense: cc-by

publisherhttps://doi.org/10.1126/scisignal.abh2071

publisherhttps://syndication.highwire.org/content/doi/10.1126/scisignal.abh2071

publisherhttps://www.science.org/doi/pdf/10.1126/scisignal.abh2071

repositoryhttps://www.osti.gov/biblio/1804146

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8432954

Fields of Study

0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

HumansManganeseMethyltransferasesS-AdenosylmethionineRecombinant ProteinsViral Nonstructural ProteinsRNA, MessengerRNA CapsRNA, ViralCrystallography, X-RaySignal TransductionAmino Acid SequenceCatalytic DomainNucleic Acid ConformationRNA StabilitySubstrate SpecificityMethylationModels, MolecularCOVID-19SARS-CoV-2

Keywords

Models, MolecularRNA CapsManganeseS-AdenosylmethionineSARS-CoV-2RNA StabilityCOVID-19MethyltransferasesViral Nonstructural ProteinsCrystallography, X-RayMethylationRecombinant ProteinsSubstrate SpecificityCatalytic DomainHumansNucleic Acid ConformationRNA, ViralAmino Acid SequenceRNA, MessengerResearch ArticlesSignal Transduction

Sustainable Development Goals

SDG 3: 3. Good health

Mn 2+ coordinates Cap-0-RNA to align substrates for efficient 2′- O -methyl transfer by SARS-CoV-2 nsp16

FAIR Checklist

Authors (9)

Funding (12 grants)

Open Access

Topics

Annotations (Europe PMC)