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Phosphorylation of RYR1 at Ser 2902 decreases Ca 2+ leak in skeletal muscle and susceptibility to malignant hyperthermia and heat stroke

Science Signaling(2025)10.1126/scisignal.adx3087Source: DataRank Database

Phosphorylation of RYR1 at Ser 2902 decreases Ca 2+ leak in skeletal muscle and susceptibility to malignant hyperthermia and heat stroke is a research paper published in Science Signaling (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (7 grants)Impact (FWCI 0.00)OA: closedTopics (34)IDs (PubMed, PMC, OpenAlex)Annotations (3)

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Findable (1/2)

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Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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Authors (10)

Chang Seok Lee ORCID,Ting Chang ORCID,Sung Yun Jung ORCID,Omar Yousif,Courtney L. Cavazos

Live enrichment

PubMed:41056385 PMC:PMC12614350 OpenAlex:https://openalex.org/W4414899992

NCI NIH HHS

Grant: P30 CA125123

NHGRI NIH HHS

Grant: UM1 HG006348

NIAMS NIH HHS

Grant: R01 AR061370

NIDDK NIH HHS

Grant: R01 DK114356

NIAMS NIH HHS

Grant: R21 AR082613

NIH HHS

Grant: S10 OD032380

NIAMS NIH HHS

Grant: R01 AR082209

FWCI

0.00

Citation Percentile

0.2%

closed

publisherhttps://www.science.org/doi/pdf/10.1126/scisignal.adx3087

journalhttps://doi.org/10.1126/scisignal.adx3087

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41056385

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12614350

repositoryhttps://digitalcommons.library.tmc.edu/baylor_docs/4995

Fields of Study

Ion channel regulation and functionAdipose Tissue and MetabolismErythrocyte Function and PathophysiologyRyanodine Receptor Calcium Release ChannelAnimalsMalignant HyperthermiaMuscle, SkeletalMicePhosphorylationCalciumHeat StrokePoint MutationCalcium SignalingSerineSarcoplasmic Reticulum

MeSH Terms

AnimalsCalciumMalignant HyperthermiaPhosphorylationSarcoplasmic ReticulumSerinePoint MutationMuscle, SkeletalHeat StrokeRyanodine Receptor Calcium Release ChannelCalcium SignalingMice

Keywords

RYR1Malignant hyperthermiaSkeletal muscleRyanodine receptorPhosphorylationEndoplasmic reticulumPoint mutation

Phosphorylation of RYR1 at Ser 2902 decreases Ca 2+ leak in skeletal muscle and susceptibility to malignant hyperthermia and heat stroke

FAIR Checklist

Authors (10)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)