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Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy

Science Translational Medicine(2021)10.1126/scitranslmed.abf0891Source: DataRank Database

Exercise triggers CAPN1-mediated AIF truncation, inducing myocyte cell death in arrhythmogenic cardiomyopathy is a research paper published in Science Translational Medicine (2021). On theSindex it has a DataRank of 0. It has been cited 92 times.

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0DataRank · unranked

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Open Access92 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (24 grants)Impact (FWCI 9.21)OA: greenTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (2)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (26)

Gizem Keceli ORCID,Andrea Carpi,Nunzianna Doti ORCID,Jacopo Agrimi ORCID,Angeliki Asimaki ORCID

Live enrichment

PubMed:33597260 PMC:PMC8936193 OpenAlex:https://openalex.org/W3129563346

National Institutes of Health

Grant: RO1 HL136918

National Institutes of Health

Grant: R01 HL063030

National Institutes of Health

Grant: R01 HL137259

National Institutes of Health

Grant: T32 AG058527

National Institutes of Health

Grant: R01 HD086026

American Heart Association

Grant: 19CDA34760185

Magic That Matters Fund

Grant: MTMF

American Heart Association

Grant: 17GRNT33670405

Fondation Leducq

Grant: 16CVD02

Maryland Stem Cell Research Fund

Grant: 2015-MSCRFI-1622

Gilead Foundation

Grant: Gilead Research Scholars in Cardiovascular Disease Fund

Fondation Leducq

Grant: 16CVD04

University of Padova Strategico Grant

Grant: DYCENDI

Heart Rhythm Society

Grant: Cardiac Pacing and Electrophysiology Fellowship Award

NHLBI NIH HHS

Grant: R01 HL156947

NHLBI NIH HHS

Grant: R01 HL134821

NHLBI NIH HHS

Grant: R01 HL136918

NHLBI NIH HHS

Grant: R01 HL138475

National Institutes of Health

Grant: 1R01HL063030-01A1

IN VIVO MURINE CARDIAC ENERGY METABOLISM AND FUNCTION

National Institutes of Health

Grant: 5R01HL138475-02

Chaperone-Mediated Autophagy in Normal Cardiac Biology and Heart Failure

National Institutes of Health

Grant: 5T32AG058527-05

Translational Aging Research Training Program

National Institutes of Health

Grant: 5R01HL137259-03

Molecular Determinants of Mitochondrial Instability and Arrhythmias

National Institutes of Health

Grant: 5R01HL136918-04

BDNF TrkB- and beta-AR signals in ischemic and non-ischemic cardiomyopathy

National Institutes of Health

Grant: 5R01HD086026-05

Regulation of Cardiac Progenitor Maintenance

FWCI

9.21

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

greenLicense: other-oa

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8936193

publisherhttps://syndication.highwire.org/content/doi/10.1126/scitranslmed.abf0891

publisherhttps://www.science.org/doi/pdf/10.1126/scitranslmed.abf0891

journalhttps://doi.org/10.1126/scitranslmed.abf0891

Fields of Study

Cardiovascular Effects of ExerciseSports injuries and preventionCardiac electrophysiology and arrhythmias0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AnimalsCalpainMitochondriaCardiomyopathiesPhysical Conditioning, AnimalCell DeathMyocytes, CardiacApoptosis Inducing FactorMice

Keywords

MyocyteCardiomyopathyCardiac myocyteMedicineCardiologyProgrammed cell deathInternal medicineBiologyHeart failureGeneticsApoptosisCell DeathCalpainApoptosis Inducing FactorAIF-mimetic peptide,CypA,MitochondriaMyocyte death,desmoglein-2 (DSG2),Micearrhythmogenic cardiomyopathy (ACM),Apoptosis Inducing Factor,Physical Conditioning, AnimalAnimalsAnimals; Cell Death; Mice; Mitochondria; Myocytes, Cardiac; Apoptosis Inducing Factor; Calpain; Cardiomyopathies; Physical Conditioning, AnimalMyocytes, CardiacCardiomyopathies

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being