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Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models

Science Translational Medicine(2022)10.1126/scitranslmed.abh3763Source: DataRank Database

Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models is a research paper published in Science Translational Medicine (2022). On theSindex it has a DataRank of 0. It has been cited 69 times.

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Scored on demand from live citation data

Open Access69 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (2 grants)Impact (FWCI 4.80)OA: greenTopics (40)IDs (PubMed, PMC, OpenAlex)Annotations (3)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (16)

Alberto Danese ORCID,Yuko Yasui,Élodie M. Richard ORCID,Jean-Charles Liévens ORCID,Simone Patergnani ORCID

Live enrichment

PubMed:35138910 PMC:PMC9516885 OpenAlex:https://openalex.org/W4210826800

Intramural NIH HHS

Grant: Z01 DA000206

Intramural NIH HHS

Grant: ZIA DA000549

FWCI

4.80

Citation Percentile

1.0%

Influential Citations

Citation Trend

2022

2023

2024

2025

2026

greenLicense: other-oa

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9516885

GREENhttps://www.ncbi.nlm.nih.gov/pmc/articles/9516885

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9516885

publisherhttps://www.science.org/doi/pdf/10.1126/scitranslmed.abh3763

journalhttps://doi.org/10.1126/scitranslmed.abh3763

Fields of Study

Pharmacological Receptor Mechanisms and EffectsEndoplasmic Reticulum Stress and DiseaseGenetics and Neurodevelopmental DisordersMedicineBiologyAnimalsCalciumFemaleHumansMaleMiceReceptors, sigmaWolfram SyndromeZebrafishSigma-1 Receptor

MeSH Terms

Sigma-1 ReceptorAnimalsCalciumFemaleHumansMaleWolfram SyndromeZebrafishReceptors, sigmaMice

Keywords

Sigma-1 receptorMitophagyEndoplasmic reticulumMitochondrionAutophagyUnfolded protein responseCell biologyChaperone (clinical)BiologyReceptorAgonistChemistryMedicineApoptosisBiochemistry

Activation of the sigma-1 receptor chaperone alleviates symptoms of Wolfram syndrome in preclinical models

FAIR Checklist

Authors (16)

Funding (2 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)