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Association of a common genetic variant with Parkinson’s disease is mediated by microglia

Science Translational Medicine(2022)10.1126/scitranslmed.abp8869Source: DataRank Database

Association of a common genetic variant with Parkinson’s disease is mediated by microglia is a research paper published in Science Translational Medicine (2022). On theSindex it has a DataRank of 0.688. It has been cited 97 times.

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0.688DataRank · unranked

Scored on demand from live citation data

Open Access97 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (12 grants)Impact (FWCI 12.82)OA: greenTopics (34)Linked Datasets (25)DataCite Reuse (25)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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DataRank Breakdown

Base Score 100%Citation Network 0%

Base Score Contribution

0.688

From this paper's citation signal

Citation Network Contribution

Citation network not refreshed for this result

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Authors (8)

Alexandra Beilina,Xylena Reed ORCID,Alice Kaganovich ORCID,Andrew Singleton ORCID,Cornelis Blauwendraat ORCID

Live enrichment

PubMed:35895835 PMC:PMC9809150 OpenAlex:https://openalex.org/W4288052118

Intramural NIH HHS

Grant: ZIA AG000947

Intramural NIH HHS

Grant: Z01 AG000949

Intramural NIH HHS

Grant: ZIA NS003154

NIA NIH HHS

Grant: P30 AG072946

NIA NIH HHS

Grant: K01 AG000947

Intramural NIH HHS

Grant: Z01 ES101986

Intramural NIH HHS

Grant: Z99 AG999999

National Institutes of Health

Grant: 1ZIAAG000947-08

Gene expression in the human brain

National Institutes of Health

Grant: 1ZIANS003154-09

Genetic characterization of atypical parkinsonism

National Institutes of Health

Grant: 3P30AG072946-02S1

Portable and modular UDS Data Collection software to increase collaboration and engagement of Alzheimer’s Disease Research Center research software engineers

National Institutes of Health

Grant: 1Z01AG000949-01

Genome wide SNP analysis in Neurological disorders

National Institutes of Health

Grant: 1Z01ES101986-03

Prospective studies on Parkinson's disease

FWCI

12.82

Citation Percentile

1.0%

Citation Trend

2021

2022

2023

2024

2025

2026

green

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/9809150

publisherhttps://www.science.org/doi/pdf/10.1126/scitranslmed.abp8869

journalhttps://doi.org/10.1126/scitranslmed.abp8869

repositoryhttps://pubmed.ncbi.nlm.nih.gov/35895835

Fields of Study

Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolismLysosomal Storage Disorders Research0301 basic medicine03 medical and health sciencesGenome-Wide Association StudyHumansLeucine-Rich Repeat Serine-Threonine Protein Kinase-2MicrogliaParkinson DiseaseSubstantia Nigra

MeSH Terms

Leucine-Rich Repeat Serine-Threonine Protein Kinase-2HumansParkinson DiseaseSubstantia NigraMicrogliaGenome-Wide Association Study

Keywords

LRRK2MicrogliaGenome-wide association studyBiologySingle-nucleotide polymorphismSubstantia nigraGeneticsGenetic associationGeneNeuroscienceMutationGenotypeImmunologyInflammationHumansParkinson DiseaseLeucine-Rich Repeat Serine-Threonine Protein Kinase-2

Sustainable Development Goals

SDG 0: Good health and well-being

Additional file 2 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

10.6084/m9.figshare.26019737.v1figshare

Additional file 2 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

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Additional file 3 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

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Additional file 3 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

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Additional file 1 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

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Additional file 1 of Single molecule array measures of LRRK2 kinase activity in serum link Parkinson’s disease severity to peripheral inflammation

10.6084/m9.figshare.26019592.v1figshare

Additional file 11 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 10 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 6 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 2 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 9 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 5 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 11 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 3 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 6 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 10 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

10.6084/m9.figshare.26759750figshare

Additional file 12 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 4 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

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Additional file 3 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

10.6084/m9.figshare.26759729.v1figshare

Additional file 8 of Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease

10.6084/m9.figshare.26759744figshare

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Association of a common genetic variant with Parkinson’s disease is mediated by microglia

FAIR Checklist

DataRank Breakdown

Authors (8)

Funding (12 grants)

Impact

Open Access

Topics

Linked Datasets (25)

Annotations (Europe PMC)

Related Papers (10)