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Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice

Science Translational Medicine(2023)10.1126/scitranslmed.ade6285Source: DataRank Database

Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice is a research paper published in Science Translational Medicine (2023). On theSindex it has a DataRank of 0. It has been cited 123 times.

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Open Access123 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (8 grants)Impact (FWCI 11.60)OA: greenTopics (41)Linked Datasets (10)DataCite Reuse (10)IDs (PubMed, PMC, OpenAlex)

FAIR Checklist

Context only (not used in score)

Findable (2/2)

Has DOI
Indexed in repositories

Accessible (1/2)

Open Access

Interoperable (2/2)

DataCite relations
Linked datasets

Reusable (0/3)

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Authors (24)

Grace Gent,Yun Chen ORCID,Nicholas Rensing,Maud Gratuze ORCID,Gregory W. Strout ORCID

Live enrichment

PubMed:37099634 PMC:PMC10449561 OpenAlex:https://openalex.org/W4367059832

NIH HHS

Grant: S10 OD032186

NCI NIH HHS

Grant: P30 CA091842

NICHD NIH HHS

Grant: P50 HD103525

NINDS NIH HHS

Grant: K08 NS109292

NINDS NIH HHS

Grant: P01 NS074969

NIGMS NIH HHS

Grant: P41 GM103422

NCATS NIH HHS

Grant: UL1 TR000448

NCATS NIH HHS

Grant: UL1 TR002345

FWCI

11.60

Citation Percentile

1.0%

Citation Trend

2023

2024

2025

2026

green

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC10449561/pdf/nihms-1923419.pdf

publisherhttps://www.science.org/doi/pdf/10.1126/scitranslmed.ade6285

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10449561

journalhttps://doi.org/10.1126/scitranslmed.ade6285

Fields of Study

Neuroinflammation and Neurodegeneration MechanismsInflammation biomarkers and pathwaysNeurological Disease Mechanisms and TreatmentsMiceAnimalsMicrogliaSleep DeprivationAmyloid beta-PeptidesAlzheimer DiseaseAmyloidosisBrainPlaque, AmyloidDisease Models, AnimalMembrane GlycoproteinsReceptors, Immunologic

MeSH Terms

Alzheimer DiseaseAmyloidosisAnimalsBrainDisease Models, AnimalMembrane GlycoproteinsReceptors, ImmunologicSleep DeprivationAmyloid beta-PeptidesMicrogliaMicePlaque, Amyloid

Keywords

TREM2Sleep deprivationSleep (system call)MicrogliaInternal medicineEndocrinologyMedicineNeuroscienceReactivity (psychology)ChemistryPsychologyCircadian rhythmInflammationPathology

Additional file 2 of Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

10.6084/m9.figshare.24540863figshare

Additional file 5 of Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

10.6084/m9.figshare.26637744.v1figshare

Additional file 3 of Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

10.6084/m9.figshare.26637738figshare

Additional file 4 of Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

10.6084/m9.figshare.26637741.v1figshare

Additional file 5 of Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

10.6084/m9.figshare.26637744figshare

Additional file 2 of Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

10.6084/m9.figshare.24540863.v1figshare

Additional file 4 of Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

10.6084/m9.figshare.26637741figshare

Additional file 3 of Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

10.6084/m9.figshare.26637738.v1figshare

Additional file 1 of Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

10.6084/m9.figshare.24540682figshare

Additional file 1 of Repeated sleep deprivation decreases the flux into hexosamine biosynthetic pathway/O-GlcNAc cycling and aggravates Alzheimer’s disease neuropathology in adult zebrafish

10.6084/m9.figshare.24540682.v1figshare