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Hepatic danger signaling triggers TREM2 + macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation

Science Translational Medicine(2024)10.1126/scitranslmed.adk1866Source: DataRank Database

Hepatic danger signaling triggers TREM2 + macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation is a research paper published in Science Translational Medicine (2024). On theSindex it has a DataRank of 0. It has been cited 62 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access62 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (5 grants)Impact (FWCI 18.21)OA: greenTopics (46)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Xiaoxue Qiu ORCID,Ziyi Meng ORCID,Tongyu Liu ORCID,Zhimin Chen ORCID,Peng Zhang ORCID

Live enrichment

PubMed:38478630 PMC:PMC12287971 OpenAlex:https://openalex.org/W4392763240

American Heart Association-American Stroke Association

Grant: 846890

NIDDK NIH HHS

Grant: R01 DK102456

NIDDK NIH HHS

Grant: R01 DK136179

NIDDK NIH HHS

Grant: P60 DK020572

NIDDK NIH HHS

Grant: P30 DK020572

FWCI

18.21

Citation Percentile

1.0%

Citation Trend

2024

2025

2026

green

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC12287971/pdf/nihms-2091918.pdf

publisherhttps://www.science.org/doi/pdf/10.1126/scitranslmed.adk1866

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12287971

journalhttps://doi.org/10.1126/scitranslmed.adk1866

Fields of Study

Liver Disease Diagnosis and TreatmentImmune cells in cancerSphingolipid Metabolism and SignalingAnimalsHumansMaleMiceInflammasomesLiverMacrophagesMembrane GlycoproteinsNLR Family, Pyrin Domain-Containing 3 ProteinNon-alcoholic Fatty Liver DiseaseReceptors, ImmunologicMembrane Proteins

MeSH Terms

NLR Family, Pyrin Domain-Containing 3 ProteinAnimalsHumansLiverMacrophagesMaleMembrane GlycoproteinsMembrane ProteinsReceptors, ImmunologicMiceInflammasomesNon-alcoholic Fatty Liver Disease

Keywords

InflammasomeSteatohepatitisFatty liverPathogenesisTREM2Liver injuryLiver diseaseNonalcoholic fatty liver diseaseMacrophageImmunologyBiologyMedicineInflammationCancer researchImmune systemDiseasePathologyInternal medicineMyeloid cells

Sustainable Development Goals

SDG 0: Good health and well-being