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Targeting the CD74 signaling axis suppresses inflammation and rescues defective hematopoiesis in RUNX1 -familial platelet disorder

Science Translational Medicine(2025)10.1126/scitranslmed.adn9832Source: DataRank Database

Targeting the CD74 signaling axis suppresses inflammation and rescues defective hematopoiesis in RUNX1 -familial platelet disorder is a research paper published in Science Translational Medicine (2025). On theSindex it has a DataRank of 0. It has been cited 16 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access16 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 6.59)OA: greenTopics (44)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (26)

Trevor Enright ORCID,Adam DuVall ORCID,Alex Chitsazan ORCID,Hsin‐Yun Lin ORCID,Aysegul Ors ORCID

Live enrichment

PubMed:39772771 PMC:PMC11912227 OpenAlex:https://openalex.org/W4406156697

NHLBI NIH HHS

Grant: F31 HL162542

NHLBI NIH HHS

Grant: R01 HL155426

NCI NIH HHS

Grant: R01 CA229875

NIDDK NIH HHS

Grant: R01 DK056638

NCI NIH HHS

Grant: U01 CA257666

NCI NIH HHS

Grant: T32 CA060441

NIDDK NIH HHS

Grant: R01 DK130895

FWCI

6.59

Citation Percentile

1.0%

Citation Trend

2025

2026

green

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC11912227/pdf/nihms-2060404.pdf

publisherhttps://www.science.org/doi/pdf/10.1126/scitranslmed.adn9832

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11912227

journalhttps://doi.org/10.1126/scitranslmed.adn9832

Fields of Study

Macrophage Migration Inhibitory FactorMyeloproliferative Neoplasms: Diagnosis and TreatmentEosinophilic Disorders and SyndromesCore Binding Factor Alpha 2 SubunitHumansSignal TransductionInflammationBlood Platelet DisordersHematopoiesisAnimalsHematopoietic Stem CellsMiceCell DifferentiationTOR Serine-Threonine KinasesCytokinesLeukemia, Myeloid, AcuteBlood Coagulation Disorders, InheritedPlatelet Disorder, Familial, with Associated Myeloid Malignancy

MeSH Terms

AnimalsBlood Platelet DisordersCell DifferentiationHematopoiesisHematopoietic Stem CellsHumansInflammationSignal TransductionLeukemia, Myeloid, AcuteCytokinesBlood Coagulation Disorders, InheritedCore Binding Factor Alpha 2 SubunitMiceTOR Serine-Threonine Kinases

Keywords

InflammationRUNX1HaematopoiesisCD74MedicinePlateletSignal transductionImmunologyCell biologyBiologyImmune systemStem cell

Sustainable Development Goals

SDG 0: Good health and well-being

Targeting the CD74 signaling axis suppresses inflammation and rescues defective hematopoiesis in RUNX1 -familial platelet disorder

FAIR Checklist

Authors (26)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)