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CRISPR activation of the ribosome-associated quality control factor ASCC3 ameliorates fragile X syndrome phenotypes in mice

Science Translational Medicine(2025)10.1126/scitranslmed.adq3551Source: DataRank Database

CRISPR activation of the ribosome-associated quality control factor ASCC3 ameliorates fragile X syndrome phenotypes in mice is a research paper published in Science Translational Medicine (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (5 grants)Impact (FWCI 2.57)OA: greenTopics (40)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (12)

Xiying Wang ORCID,Jie Pan ORCID,Danish Khan ORCID,Sopida Pimcharoen,Yong‐Jie Zhang ORCID

Live enrichment

PubMed:41061044 PMC:PMC13069991 OpenAlex:https://openalex.org/W4414941385

NIA NIH HHS

Grant: R01 AG089752

NINDS NIH HHS

Grant: R37 NS083417

NIMH NIH HHS

Grant: R21 MH127340

NIGMS NIH HHS

Grant: R35 GM153301

NINDS NIH HHS

Grant: R01 NS084412

FWCI

2.57

Citation Percentile

0.9%

Citation Trend

2025

2026

green

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC13069991/pdf/nihms-2154644.pdf

publisherhttps://www.science.org/doi/pdf/10.1126/scitranslmed.adq3551

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC13069991/

journalhttps://doi.org/10.1126/scitranslmed.adq3551

Fields of Study

Genetics and Neurodevelopmental DisordersRNA modifications and cancerAdvanced biosensing and bioanalysis techniquesAnimalsFragile X SyndromeHumansFragile X Messenger Ribonucleoprotein 1PhenotypeRibosomesMiceMice, KnockoutClustered Regularly Interspaced Short Palindromic RepeatsNeuronsDisease Models, AnimalInduced Pluripotent Stem CellsMale

MeSH Terms

AnimalsDisease Models, AnimalFragile X SyndromeHumansMaleNeuronsPhenotypeRibosomesMice, KnockoutMiceFragile X Mental Retardation ProteinFragile X Messenger Ribonucleoprotein 1Induced Pluripotent Stem CellsClustered Regularly Interspaced Short Palindromic Repeats

Keywords

Fragile X syndromeRibonucleoproteinMessenger RNAPhenotypeAutism spectrum disorderProtein subunitPolysomeCRISPRSynaptogenesisRibosome

CRISPR activation of the ribosome-associated quality control factor ASCC3 ameliorates fragile X syndrome phenotypes in mice

FAIR Checklist

Authors (12)

Funding (5 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)