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The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem

Antimicrobial Agents and Chemotherapy(2024)10.1128/aac.00687-24Source: DataRank Database

The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem is a research paper published in Antimicrobial Agents and Chemotherapy (2024). On theSindex it has a DataRank of 0. It has been cited 6 times.

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Open Access6 citations

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Enrichment:Funding (5 grants)Topics (15)IDs (PubMed, PMC)Annotations (1)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (9)

Anna Cmolik,Christopher R. Bethel,Yoshikazu Ishii ORCID,Salvador I. Drusin ORCID,Diego M. Moreno ORCID

Live enrichment

PubMed:39023262 PMC:PMC11304723

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: UM1AI104681

U.S. Department of Veterans Affairs

Grant: 1I01BX005307

Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación

Grant: PICT-2020-03769

Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación

Grant: PICT-2020-00031

BLRD VA

Grant: I01 BX005307

MeSH Terms

Escherichia coliCarbapenemsAzetidinesThiazolesbeta-LactamasesAnti-Bacterial AgentsMicrobial Sensitivity TestsCatalytic DomainStructure-Activity RelationshipMolecular Dynamics SimulationMeropenem

Keywords

Metallo-β-lactamaseIMPCarbapenemaseTebipenem

The interaction of the azetidine thiazole side chain with the active site loop (ASL) 3 drives the evolution of IMP metallo-β-lactamase against tebipenem

FAIR Checklist

Authors (9)

Funding (5 grants)

Topics

Annotations (Europe PMC)