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Sterilizing activity of spectinamide MBX-4888A when replacing linezolid in the Nix-TB regimen in the relapsing BALB/c mouse model of tuberculosis

Antimicrobial Agents and Chemotherapy(2025)10.1128/aac.01183-25Source: DataRank Database

Sterilizing activity of spectinamide MBX-4888A when replacing linezolid in the Nix-TB regimen in the relapsing BALB/c mouse model of tuberculosis is a research paper published in Antimicrobial Agents and Chemotherapy (2025). On theSindex it has a DataRank of 0.

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Enrichment:Funding (2 grants)Impact (FWCI 0.00)OA: hybridTopics (45)IDs (PubMed, PMC, OpenAlex)

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Findable (1/2)

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Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (14)

Michaël Scherman ORCID,Firat Kaya ORCID,Samanthi L. Waidyarachchi ORCID,Jiuyu Liu ORCID,Joel N. Rushefsky

Live enrichment

PubMed:41025648 PMC:PMC12587623 OpenAlex:https://openalex.org/W4414662564

NIAID NIH HHS

Grant: R01 AI090810

NIAID NIH HHS

Grant: R44 AI098271

FWCI

0.00

Citation Percentile

0.3%

hybridLicense: cc-by

journalhttps://doi.org/10.1128/aac.01183-25

HYBRIDhttps://doi.org/10.1128/aac.01183-25

publisherhttps://doi.org/10.1128/aac.01183-25

repositoryhttps://pubmed.ncbi.nlm.nih.gov/41025648

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12587623

Fields of Study

Tuberculosis Research and EpidemiologyCancer therapeutics and mechanismsMycobacterium research and diagnosisMedicineAnimalsLinezolidAntitubercular AgentsMiceMice, Inbred BALB CMycobacterium tuberculosisDiarylquinolinesSpectinomycinFemaleDisease Models, AnimalDrug Therapy, CombinationNitroimidazolesMicrobial Sensitivity TestsAdamantaneEthylenediamines

MeSH Terms

LinezolidSpectinomycinAdamantaneAnimalsAntitubercular AgentsDisease Models, AnimalDrug Therapy, CombinationEthylenediaminesFemaleMice, Inbred BALB CMicrobial Sensitivity TestsMycobacterium tuberculosisNitroimidazolesMiceDiarylquinolines

Keywords

LinezolidRegimenTuberculosisAdverse effectAntibacterial agentAntibioticsBalb/CRelapseBedaquilinePretomanidSpectinamide