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Broken beyond repair: TA system ParE toxins mediate effective gyrase inhibition without driving resistance

Journal of Bacteriology(2025)10.1128/jb.00416-24Source: DataRank Database

Broken beyond repair: TA system ParE toxins mediate effective gyrase inhibition without driving resistance is a research paper published in Journal of Bacteriology (2025). On theSindex it has a DataRank of 0. It has been cited 3 times.

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Open Access3 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (6 grants)Impact (FWCI 2.72)OA: goldTopics (48)IDs (PubMed, PMC, OpenAlex)Annotations (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (4)

Shengfeng Ruan ORCID,Michelle Holt,Christina R. Bourne ORCID,Chih-Han Tu

Live enrichment

PubMed:40029095 PMC:PMC11925232 OpenAlex:https://openalex.org/W4408112591

U.S. Department of Defense

Grant: PR192335

HHS | National Institutes of Health

Grant: P20GM103640,P30GM145423

NIGMS NIH HHS

Grant: P30 GM145423

NIGMS NIH HHS

Grant: P20 GM103640

National Institutes of Health

Grant: 1P30GM145423-01

Oklahoma COBRE in Structural Biology

National Institutes of Health

Grant: 1P20GM103640-01

Structural characterization of gamma-glutamyl transferase enzymes

FWCI

2.72

Citation Percentile

0.9%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://journals.asm.org/doi/pdf/10.1128/jb.00416-24?download=true

publisherhttps://journals.asm.org/doi/pdf/10.1128/jb.00416-24?download=true

publisherhttps://journals.asm.org/doi/pdf/10.1128/jb.00416-24

journalhttps://doi.org/10.1128/jb.00416-24

repositoryhttps://pubmed.ncbi.nlm.nih.gov/40029095

Fields of Study

Bacterial Genetics and BiotechnologyEscherichia coli research studiesVibrio bacteria research studies0301 basic medicine03 medical and health sciences

MeSH Terms

Toxin-Antitoxin SystemsAnti-Bacterial AgentsBacterial ProteinsBacterial ToxinsMicrobial Sensitivity TestsMutationMycobacterium tuberculosisPseudomonas aeruginosaVibrio choleraeDrug Resistance, BacterialDNA GyraseDNA Topoisomerase IVTopoisomerase II Inhibitors

Keywords

DNA gyraseBiologyMicrobiologyTopoisomerase IVTopoisomeraseVibrio choleraeDNA damageDNA supercoilDNAGeneticsEscherichia coliDNA replicationBacteriaGenePare ToxinAntimicrobial SusceptibilityToxin AntitoxinMutation FrequencyBacterial Cell ViabilityGyrase InhibitionDNA Topoisomerase IVBacterial ProteinsBacterial ToxinsDrug Resistance, BacterialMutationTopoisomerase II InhibitorsToxin-Antitoxin SystemsMicrobial Sensitivity TestsResearch ArticleAnti-Bacterial Agents

Broken beyond repair: TA system ParE toxins mediate effective gyrase inhibition without driving resistance

FAIR Checklist

Authors (4)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)