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A Maraviroc-Resistant HIV-1 with Narrow Cross-Resistance to Other CCR5 Antagonists Depends on both N-Terminal and Extracellular Loop Domains of Drug-Bound CCR5

Journal of Virology(2010)10.1128/jvi.01109-10Source: DataRank Database

A Maraviroc-Resistant HIV-1 with Narrow Cross-Resistance to Other CCR5 Antagonists Depends on both N-Terminal and Extracellular Loop Domains of Drug-Bound CCR5 is a research paper published in Journal of Virology (2010). On theSindex it has a DataRank of 4.8. It has been cited 107 times, with 101 citing works in its 1-hop citation network.

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4.8DataRank · unranked

Scored on demand from live citation data

107 citations · 101 citing works in its network

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (1 grants)Impact (FWCI 5.51)OA: greenTopics (70)IDs (PubMed, PMC, OpenAlex)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (0/2)

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 15%Citation Network 85%

Base Score Contribution

0.702

From this paper's citation signal

Citation Network Contribution

4.1

From 95 citing papers with measurable signal

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Authors (11)

Craig B. Wilen ORCID,Chukwuka A. Didigu,Rohini Sinha,Jessamina E. Harrison,Caroline Agrawal-Gamse

Live enrichment

PubMed:20702642 PMC:PMC2950574 OpenAlex:https://openalex.org/W2164681352

NIAID NIH HHS

Grant: P01 AI090935

FWCI

5.51

Citation Percentile

1.0%

Citation Trend

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greenLicense: https://journals.asm.org/non-commercial-tdm-license

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/2950574

publisherhttps://journals.asm.org/doi/pdf/10.1128/JVI.01109-10

journalhttps://doi.org/10.1128/jvi.01109-10

repositoryhttps://pubmed.ncbi.nlm.nih.gov/20702642

Fields of Study

HIV Research and TreatmentHIV/AIDS drug development and treatmentImmune Cell Function and InteractionBase SequenceBinding SitesCCR5 Receptor AntagonistsCell LineCohort StudiesCyclohexanesDNA PrimersDrug Resistance, ViralHIV Envelope Protein gp120HIV Fusion InhibitorsHIV InfectionsHIV-1HumansIn Vitro TechniquesMaravirocModels, BiologicalMutant ProteinsMutationPeptide FragmentsProtein Structure, TertiaryReceptors, CCR5Triazoles

MeSH Terms

MaravirocBase SequenceBinding SitesCell LineCyclohexanesHumansModels, BiologicalMutationPeptide FragmentsTriazolesCohort StudiesHIV-1HIV InfectionsHIV Envelope Protein gp120Protein Structure, TertiaryDNA PrimersReceptors, CCR5HIV Fusion InhibitorsDrug Resistance, ViralMutant ProteinsCCR5 Receptor AntagonistsIn Vitro Techniques

Keywords

MaravirocCCR5 receptor antagonistBiologyEnfuvirtideVirologyEntry inhibitorDrug resistanceViral entryExtracellularVirusAntagonistV3 loopViral replicationGp41Human immunodeficiency virus (HIV)ReceptorCell biologyImmunologyPeptide sequenceGeneticsChemokine receptorGeneChemokine

Sustainable Development Goals

SDG 0: Good health and well-being