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Acarbose impairs gut Bacteroides growth by targeting intracellular glucosidases

Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Acarbose impairs gut Bacteroides growth by targeting intracellular glucosidases

mBio(2024)10.1128/mbio.01506-24Source: DataRank Database

Acarbose impairs gut Bacteroides growth by targeting intracellular glucosidases is a research paper published in mBio (2024). On theSindex it has a DataRank of 0.280. It has been cited 5 times, with 5 citing works in its 1-hop citation network.

N/A

0.280DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access5 citations · 5 citing works in its network

Cite:

Data availability

Repositories this paper deposited data in (declared in PubMed).

BioProjectPRJNA1107240

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (16 grants)Impact (FWCI 0.96)OA: goldTopics (46)IDs (PubMed, OpenAlex)

FAIR Checklist

Context only (not used in score)

FFindable (1/2)

Has DOI

AAccessible (1/2)

Open Access

IInteroperable (0/2)

RReusable (0/3)

FAIR checklist signals are shown for context only and do not affect DataRank scoring.

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DataRank Breakdown

Base Score 96%Citation Network 4%

Base Score Contribution

0.269

From this paper's citation signal

Citation Network Contribution

0.0114

From 1 citing papers with measurable signal

Learn more about DataRank methodology →

Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 5 citers.

Emerging gut microbial glycoside hydrolase inhibitors
RSC Chemical Biology20259 citations172 referencesContributes 0.013
Bioassay-guided evaluation of a potent dual inhibitor of host and gut microbial α-glucosidases from Galla chinensis: mechanism insights and in silico studies
Fitoterapia20250 citations40 referencesContributes 0.000
Cyclitols and Aminocyclitols as Signals: Their Roles in Supporting Ecosystems and Promoting Human Health
Journal of Natural Products20260 citations125 referencesContributes 0.000
Microbiota and Aging Solutions
20260 citations118 referencesContributes 0.000
The relationship between diabetic retinopathy and intestinal microbiota: a systematic review and meta analysis
International Ophthalmology20260 citations76 referencesContributes 0.000

Authors (7)

Adeline L. Morris,Nicholas A. Pudlo ORCID,A. Hopkins,Eric C. Martens ORCID,Jonathan L. Golob ORCID

Live enrichment

PubMed:39565129 OpenAlex:https://openalex.org/W4404536661

HHS | National Institutes of Health

Grant: F32-AT011278

HHS | National Institutes of Health

Grant: R01-GM118475

HHS | National Institutes of Health

Grant: R01-DK125445

HHS | National Institutes of Health

Grant: R01-DK118024

HHS | National Institutes of Health

Grant: P01-HL149633

University of Michigan

Grant: Pandemic Research Recovery

National Institutes of Health

Grant: 5P01HL149633-03

Host and Microbial Metabolism in Graft versus Host Disease

National Institutes of Health

Grant: 5R01DK118024-06

Dietary fiber and soy protein-based microbiome metabolites for IBD prevention

National Institutes of Health

Grant: 1F32AT011278-01A1

The Influence of the Glucoamylase Inhibitor Acarbose on Bacteroidetes Starch Utilization and Fitness in the Human Gut

National Institutes of Health

Grant: 5R01GM118475-05

Assembly of a model glycan uptake system from a symbiotic human gut bacterium

National Institutes of Health

Grant: 5R01DK125445-04

Unraveling the enzymatic pathway of gut bacterial mucus degradation to treat inflammation

NIDDK NIH HHS

Grant: R01 DK125445

NCCIH NIH HHS

Grant: F32 AT011278

NIGMS NIH HHS

Grant: R01 GM118475

NIDDK NIH HHS

Grant: R01 DK118024

NHLBI NIH HHS

Grant: P01 HL149633

FWCI

0.96

Citation Percentile

0.7%

Citation Trend

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1128/mbio.01506-24

publisherhttps://doi.org/10.1128/mbio.01506-24

publisherhttps://journals.asm.org/doi/pdf/10.1128/mbio.01506-24

repositoryhttps://pubmed.ncbi.nlm.nih.gov/39565129

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/11633381

Fields of Study

Gut microbiota and healthClostridium difficile and Clostridium perfringens researchProbiotics and Fermented Foods0301 basic medicine0303 health sciences03 medical and health sciencesAcarboseBacteroidesBacteroides thetaiotaomicronStarchGastrointestinal MicrobiomeGlucosidasesHumansBacterial ProteinsBacteroides ovatus

MeSH Terms

Gastrointestinal MicrobiomeBacteroides thetaiotaomicronBacterial ProteinsBacteroidesGlucosidasesHumansStarchAcarbose

Keywords

AcarboseBacteroidesStarchBiochemistryBiologyBacteroides fragilisMicrobiologyChemistryEnzymeBacteriaGeneticsglucosidaseglycoside hydrolase family 97alpha-amylaseQR1-502Gastrointestinal MicrobiomeBacteroides thetaiotaomicronBacterial ProteinsBacteroidotaHumansglycoside hydrolase family 13GlucosidasesResearch Article

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