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Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity

mBio(2021)10.1128/mbio.01743-21Source: DataRank Database

Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity is a research paper published in mBio (2021). On theSindex it has a DataRank of 0. It has been cited 10 times.

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Open Access10 citations

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

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Enrichment:Funding (6 grants)Impact (FWCI 1.10)OA: goldTopics (69)IDs (PubMed, PMC, OpenAlex)Annotations (4)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (8)

Chengzi I. Kaku ORCID,Jérémy Dufloo ORCID,Timothée Bruel ORCID,Olivier Schwartz ORCID,David A. Spencer ORCID

Live enrichment

PubMed:34634936 PMC:PMC8510540 OpenAlex:https://openalex.org/W3206779894

HHS | National Institutes of Health

Grant: R01AI131975

HHS | National Institutes of Health

Grant: R01AI129801

Agence Nationale de Recherches sur le Sida et les Hépatites Virales

Grant: ANR-10-LABX-77

National Institutes of Health

Grant: 5R01AI131975-02

Directing Antibody Effector Activity via Controlled IgG Subclass Switching

National Institutes of Health

Grant: 5R01AI129801-05

Using monoclonal antibody Fc variants in strategies to eliminate HIV reservoirs

Fondation pour la Recherche Médicale

FWCI

1.10

Citation Percentile

0.7%

Citation Trend

2022

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1128/mbio.01743-21

publisherhttps://doi.org/10.1128/mbio.01743-21

publisherhttps://journals.asm.org/doi/pdf/10.1128/mBio.01743-21

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34634936

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/8510540

Fields of Study

HIV Research and TreatmentMonoclonal and Polyclonal Antibodies ResearchImmune Cell Function and Interaction0301 basic medicine03 medical and health sciences0303 health sciencesAnimalsAntibodies, NeutralizingBroadly Neutralizing AntibodiesComplement C1qComplement System ProteinsHEK293 CellsHIV AntibodiesHIV InfectionsHIV-1HumansImmunoglobulin GMacaca mulatta

MeSH Terms

Broadly Neutralizing AntibodiesAnimalsComplement System ProteinsHumansImmunoglobulin GMacaca mulattaHIV AntibodiesHIV-1HIV InfectionsComplement C1qAntibodies, NeutralizingHEK293 Cells

Keywords

AntibodyImmunologyContext (archaeology)Mechanism (biology)VirologyComplement (music)Neutralizing antibodyHuman immunodeficiency virus (HIV)Function (biology)BiologyMedicineCell biologyPhenotypeGeneticsComplementHuman immunodeficiency virusHIVMechanism of actionFCC1qCdcViral LysisAntibody-mediated PreventionHIV InfectionsHIV AntibodiesMicrobiologyAnimalsHumans[SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/VirologyComplement C1qComplement System ProteinsAntibodies, NeutralizingMacaca mulattaQR1-502HEK293 CellsImmunoglobulin GHIV-1Broadly Neutralizing AntibodiesResearch Article

Sustainable Development Goals

SDG 0: Good health and well-being

Revisiting an IgG Fc Loss-of-Function Experiment: the Role of Complement in HIV Broadly Neutralizing Antibody b12 Activity

FAIR Checklist

Authors (8)

Funding (6 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)