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The Histidine Ammonia Lyase of Trypanosoma cruzi Is Involved in Acidocalcisome Alkalinization and Is Essential for Survival under Starvation Conditions

mBio(2021)10.1128/mbio.01981-21Source: DataRank Database

The Histidine Ammonia Lyase of Trypanosoma cruzi Is Involved in Acidocalcisome Alkalinization and Is Essential for Survival under Starvation Conditions is a research paper published in mBio (2021). On theSindex it has a DataRank of 0. It has been cited 8 times.

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0DataRank · unranked

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Open Access8 citations

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datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (7 grants)Impact (FWCI 0.43)OA: goldTopics (42)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (5)

Cristina Azevedo,Paul W. Denny,Adolfo Saiardi ORCID,Roberto Docampo ORCID,Brian S. Mantilla ORCID

Live enrichment

PubMed:34724827 PMC:PMC8561398 OpenAlex:https://openalex.org/W3210937215

UKRI | Medical Research Council

Grant: MC_UU_12018/4 and MR/T028904/1

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: AI108222

UKRI Grand Challenge Research Fund

Grant: MR/P027989/1

A Global Network for Neglected Tropical Diseases

NIAID NIH HHS

Grant: R01 AI108222

Medical Research Council

Grant: MC_UU_12018/4

Dissecting inositol pyrophosphates signalling

Medical Research Council

Grant: MR/T028904/1

Regulation of metabolism by inositol pyrophosphates

National Institutes of Health

Grant: 1R01AI108222-01A1

Calcium signaling in Trypanosoma brucei

FWCI

0.43

Citation Percentile

0.6%

Citation Trend

2022

2023

2025

goldLicense: cc-by

journalhttps://doi.org/10.1128/mbio.01981-21

publisherhttps://doi.org/10.1128/mbio.01981-21

publisherhttps://journals.asm.org/doi/pdf/10.1128/mBio.01981-21

repositoryhttps://pubmed.ncbi.nlm.nih.gov/34724827

repositoryhttp://dro.dur.ac.uk/34425/

Fields of Study

Trypanosoma species research and implicationsLysosomal Storage Disorders ResearchResearch on Leishmaniasis Studies0301 basic medicine0303 health sciences03 medical and health sciences

MeSH Terms

AlkaliesCalciumHistidine Ammonia-LyaseHistidineHumansPolyphosphatesTrypanosoma cruziChagas DiseaseOrganellesProtozoan ProteinsAmino Acid Motifs

Keywords

Trypanosoma cruziHistidineVacuoleCytosolOrganelleYeastEnzymeSaccharomyces cerevisiaePolyphosphateAlkalinizationAcidocalcisomeHistidine Ammonia LyaseOrganelles570Amino Acid MotifsProtozoan ProteinsAlkaliesMicrobiologyQR1-502PolyphosphatesHumansCalciumChagas DiseaseHistidine Ammonia-LyaseResearch Article

Sustainable Development Goals

SDG 2: 2. Zero hungerSDG 3: 3. Good health

The Histidine Ammonia Lyase of Trypanosoma cruzi Is Involved in Acidocalcisome Alkalinization and Is Essential for Survival under Starvation Conditions

FAIR Checklist

Authors (5)

Funding (7 grants)

Impact

Open Access

Topics

Annotations (Europe PMC)