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SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells

mBio(2022)10.1128/mbio.02415-22Source: DataRank Database

SARS-CoV-2 Diverges from Other Betacoronaviruses in Only Partially Activating the IRE1α/XBP1 Endoplasmic Reticulum Stress Pathway in Human Lung-Derived Cells is a research paper published in mBio (2022). On theSindex it has a DataRank of 0. It has been cited 29 times.

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Scored on demand from live citation data

Open Access29 citations

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Linked data & code

geo gen rrid

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (19 grants)Impact (FWCI 2.80)OA: goldTopics (80)IDs (PubMed, PMC, OpenAlex)Annotations (3)SDGs (2)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (25)

David M. Renner ORCID,Diane Silva ORCID,Dongbo Yang ORCID,Nicholas A. Parenti ORCID,Kaeri M. Medina ORCID

Live enrichment

PubMed:36125275 PMC:PMC9600248 OpenAlex:https://openalex.org/W4296782458

HHS | NIH | National Cancer Institute

Grant: R01CA219815

HHS | NIH | National Eye Institute

Grant: R01EY027810

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: R01AI140442

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: T32AI055400

HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases

Grant: U01DK127786

HHS | NIH | National Institute of General Medical Sciences

Grant: R01 GM121735

U.S. Department of Veterans Affairs

Grant: 2I01BX005411

BLRD VA

Grant: I01 BX005411

BLRD VA

Grant: I01 BX001176

NCI NIH HHS

Grant: P30 CA014599

National Institutes of Health

Grant: 1R01CA219815-01A1

Targeting the Unfolded Protein Response in PanNETs

National Institutes of Health

Grant: 3P30CA014599-36S1

Cancer Center Support Grant

National Institutes of Health

Grant: 1ZIADK013039-04

Molecular modeling of soluble proteins

National Institutes of Health

Grant: 5R01GM121735-03

Regulation of RKIP Function

National Institutes of Health

Grant: 4T32AI055400-14

Training in Emerging Infectious Diseases

National Institutes of Health

Grant: 5R01AI140442-02

MERS coronavirus: antagonism of double-stranded RNA induced host response by accessory proteins

National Institutes of Health

Grant: 1I01BX005411-01

COVID-19: Understanding The Role of Corona Virus InducedDisruption Of Alveolar Type 2 Cell Function And SurfactantHomeostasis In The Pathogenesis Of COVID-19 AcuteRespiratory Distress Syndrome

National Institutes of Health

Grant: 5R01EY027810-02

Role of the Unfolded Protein Response in Photoreceptor Degeneration

National Institutes of Health

Grant: 5U01DK127786-04

The Integrated Stress Response in Human Islets During Early T1D

FWCI

2.80

Citation Percentile

0.9%

Citation Trend

2023

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1128/mbio.02415-22

publisherhttps://doi.org/10.1128/mbio.02415-22

publisherhttps://journals.asm.org/doi/pdf/10.1128/mbio.02415-22

repositoryhttps://pubmed.ncbi.nlm.nih.gov/36125275

repositoryhttps://www.osti.gov/biblio/2469989

Fields of Study

Endoplasmic Reticulum Stress and DiseaseRNA regulation and diseaseCalcium signaling and nucleotide metabolism0301 basic medicine03 medical and health sciencesAnimalsMiceHumansEndoribonucleasesEndoplasmic Reticulum StressSARS-CoV-2InositolProtein Serine-Threonine KinasesCOVID-19Middle East Respiratory Syndrome CoronavirusRibonucleasesTranscription FactorsRNA, MessengerLungInterferonsX-Box Binding Protein 1

MeSH Terms

X-Box Binding Protein 1COVID-19SARS-CoV-2AnimalsEndoribonucleasesHumansInositolInterferonsLungRibonucleasesRNA, MessengerTranscription FactorsProtein Serine-Threonine KinasesMiceEndoplasmic Reticulum StressMiddle East Respiratory Syndrome Coronavirus

Keywords

Endoplasmic reticulumCoronavirusUnfolded protein responseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)XBP1Coronavirus disease 2019 (COVID-19)VirologyBetacoronavirus2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirusLungBiologyImmunologyDiseaseMedicineCell biologyGeneticsGenePathologyInfectious disease (medical specialty)RNAInternal medicineOC43Mers-covIre1α PathwaySars-cov-2X-Box Binding Protein 1Protein Serine-Threonine KinasesMicrobiologyMiceRibonucleasesEndoribonucleasesAnimalsHumansRNA, MessengerCOVID-19Endoplasmic Reticulum StressQR1-502Middle East Respiratory Syndrome CoronavirusInterferonsInositolResearch ArticleTranscription Factors

Sustainable Development Goals

SDG 3: 3. Good healthSDG 0: Good health and well-being