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Avidity and variable domain spacing strongly influence the therapeutic potency of bispecific antibodies against Crimean-Congo hemorrhagic fever virus

mBio(2025)10.1128/mbio.03202-24Source: DataRank Database

Avidity and variable domain spacing strongly influence the therapeutic potency of bispecific antibodies against Crimean-Congo hemorrhagic fever virus is a research paper published in mBio (2025). On theSindex it has a DataRank of 0. It has been cited 1 time.

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Enrichment:Funding (5 grants)OA: goldTopics (17)IDs (PubMed, PMC)Annotations (3)

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Reusable (0/3)

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Authors (19)

Stephanie R. Monticelli ORCID,Ariel S. Wirchnianski ORCID,Dafna M. Abelson ORCID,Ana I. Kuehne,Russell R. Bakken ORCID

Live enrichment

PubMed:40237506 PMC:PMC12077110

National Institutes of Health

Grant: U19AI142777

National Institutes of Health

Grant: T32GM00728,T32GM149364

National Institutes of Health

Grant: T32AI070117

NIGMS NIH HHS

Grant: T32 GM149364

NIGMS NIH HHS

Grant: T32 GM007288

goldLicense: cc-by

publisherhttps://doi.org/10.1128/mbio.03202-24

publisherhttps://journals.asm.org/doi/pdf/10.1128/mbio.03202-24

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/12077110

repositoryhttps://doaj.org/article/f4b5950fdb5f45b2b6dc46e079a79752

Europe_PMChttps://europepmc.org/articles/PMC12077110

MeSH Terms

AnimalsMice, Inbred BALB CHumansMiceHemorrhagic Fever Virus, Crimean-CongoHemorrhagic Fever, CrimeanAntibodies, BispecificAntibodies, MonoclonalAntibodies, ViralNeutralization TestsAntibody AffinityFemaleAntibodies, Neutralizing

Keywords

Monoclonal antibodyBispecific antibodyImmunotherapyCrimean-congo Hemorrhagic Fever Virus

Avidity and variable domain spacing strongly influence the therapeutic potency of bispecific antibodies against Crimean-Congo hemorrhagic fever virus

FAIR Checklist

Authors (19)

Funding (5 grants)

Open Access

Topics

Annotations (Europe PMC)