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The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function

mBio(2023)10.1128/mbio.03560-22Source: DataRank Database

The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function is a research paper published in mBio (2023). On theSindex it has a DataRank of 0. It has been cited 18 times.

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0DataRank · unranked

Scored on demand from live citation data

Open Access18 citations

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Linked data & code

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (18 grants)OA: goldTopics (36)IDs (PubMed, PMC)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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Authors (15)

Tung Dinh ORCID,Lev Levintov ORCID,Arun S. Annamalai ORCID,Juan S. Rey ORCID,Lorenzo Briganti ORCID

Live enrichment

PubMed:36744954 PMC:PMC9973045

Medical Research Council

Grant: CC2058

Medical Research Council

Grant: CC2029

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: P50AI150481

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: U54AI170791

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: R37AI039394

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: R01AI141327

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: R01AI143649

HHS | NIH | National Institute of Allergy and Infectious Diseases

Grant: U54AI150472

HHS | NIH | National Institute of General Medical Sciences

Grant: P20GM104316

The Francis Crick Institute

Grant: 10178

National Institutes of Health

Grant: 5R01AI143649-05

Multimeric HIV-1 Integrase Inhibitors

National Institutes of Health

Grant: 1U54AI170791-01

Pittsburgh Center for HIV Protein Interactions (PCHPI)

National Institutes of Health

Grant: 7U54AI150472-10

HIV Interactions In Viral Evolution

Wellcome Trust

Grant: unidentified

unidentified

National Institutes of Health

Grant: 3P50AI150481-13S1

MicroCal PEAQ-DSC

National Institutes of Health

Grant: 3P20GM104316-10S1

Discovery of Molecular Probes and Therapeutic Leads

National Institutes of Health

Grant: 5R37AI039394-23

Biochemical Mechanism of HIV DNA Integration

National Institutes of Health

Grant: 5R01AI141327-07

Structural and Chemical Analysis of Highly Potent ALLINI Platform

goldLicense: cc-by

publisherhttps://doi.org/10.1128/mbio.03560-22

publisherhttps://journals.asm.org/doi/pdf/10.1128/mbio.03560-22

repositoryhttps://pmc.ncbi.nlm.nih.gov/articles/PMC9973045/pdf/mbio.03560-22.pdf

repositoryhttps://doaj.org/article/18637d366ddf46828152a6725c46c973

repositoryhttps://figshare.com/articles/journal_contribution/The_drug-induced_interface_that_drives_HIV-1_integrase_hypermultimerization_and_loss_of_function_/22193668

Fields of Study

0301 basic medicine03 medical and health sciences0303 health sciences

MeSH Terms

HumansHIV InfectionsHIV IntegraseHIV Integrase InhibitorsAntiviral AgentsAllosteric Regulation

Keywords

HIV-1IntegraseAntiretroviral DrugsAllosteric InhibitorLedginAlliniBi-dPirmitegravirStp0404Model organisms570good health and well-beingHIV InfectionsInfectious DiseaseHIV IntegraseBiochemistry & ProteomicsMicrobiologyAntiviral AgentsAllosteric Regulation616HumansHIV Integrase InhibitorsGenome Integrity & RepairQR1-502Cell Cycle & ChromosomesResearch ArticleStructural Biology & Biophysics

Sustainable Development Goals

SDG 3: 3. Good health