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Fostemsavir resistance-associated polymorphisms in HIV-1 subtype C in a large cohort of treatment-naïve and treatment-experienced individuals in Botswana

Microbiology Spectrum(2023)10.1128/spectrum.01251-23Source: DataRank Database

Fostemsavir resistance-associated polymorphisms in HIV-1 subtype C in a large cohort of treatment-naïve and treatment-experienced individuals in Botswana is a research paper published in Microbiology Spectrum (2023). On theSindex it has a DataRank of 0.423. It has been cited 7 times, with 7 citing works in its 1-hop citation network.

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0.423DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access7 citations · 7 citing works in its network

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Data availability

Repositories this paper deposited data in (declared in PubMed).

ClinicalTrials.govNCT01965470

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›Methodology & internals

datarank_citation_only_1hop_v6· scope data_onlyMethodology

Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring

Enrichment:Funding (15 grants)Impact (FWCI 0.86)OA: goldTopics (56)IDs (PubMed, PMC, OpenAlex)Annotations (1)SDGs (1)

FAIR Checklist

Context only (not used in score)

Findable (1/2)

Has DOI

Accessible (1/2)

Open Access

Interoperable (0/2)

Reusable (0/3)

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DataRank Breakdown

Base Score 74%Citation Network 26%

Base Score Contribution

0.312

From this paper's citation signal

Citation Network Contribution

0.111

From 5 citing papers with measurable signal

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Top 5 citers driving the network score

Ranked by each citer's contribution to N(p) — log1p(C_q) divided by its reference count — out of 7 citers.

Investigation of Natural Resistance to Fostemsavir and Lenacapavir in Naïve Primary Infections by Ultra-Deep Sequencing of near Full-Length HIV-1 Genomes
Viruses20251 citations14 referencesContributes 0.050
Mechanism of action, resistance, interaction, pharmacokinetics, pharmacodynamics, and safety of fostemsavir
BMC Infectious Diseases202411 citations73 referencesContributes 0.034
30 years of HIV therapy: Current and future antiviral drug targets
Virology202426 citations137 referencesContributes 0.024
Fostemsavir resistance in clinical context: a narrative review
Therapeutic Advances in Infectious Disease20251 citations44 referencesContributes 0.016
Comprehensive Mapping of the Virus and Host Factors that Guide the Paths of HIV-1 Escape from a Therapeutic
bioRxiv (Cold Spring Harbor Laboratory)20251 citations89 referencesContributes 0.008

Authors (19)

Botshelo Radibe,Wonderful T. Choga ORCID,Ontlametse T. Bareng ORCID,Natasha O. Moraka ORCID,Dorcas Maruapula ORCID

Live enrichment

PubMed:37823653 PMC:PMC10714836 OpenAlex:https://openalex.org/W4387563443

Bill and Melinda Gates Foundation

Grant: INV- 033558

HHS | NIH | Fogarty International Center

Grant: 5D43TW009610-09

Training in HIV/AIDS Prevention and Treatment Research in Botswana

FIC NIH HHS

Grant: D43 TW009610

CGH CDC HHS

Grant: U2G GH001911

NHGRI NIH HHS

Grant: U41 HG006941

Wellcome Trust

Grant: 107752/Z/15/Z

FIC NIH HHS

Grant: K43 TW012350

European & Developing Countries Clinical Trials Partnership (EDCTP)

Grant: CSA2020NoE-3104

CGH CDC HHS

Grant: U01 GH000447

National Institutes of Health

Grant: 3U41HG006941-02S2

H3ABioNet: a sustainable African Bioinformatics Network for H3Africa

National Institutes of Health

Grant: 5U01GH000447-04

Impact Evaluation of Combination HIV Prevention Interventions in Botswana

Wellcome Trust

Grant: 107752

Sub-Saharan African Network for TB/HIV research Excellence (SANTHE)

National Institutes of Health

Grant: 5U2GGH001911-03

GH16-002, Botswana: Impact Evaluation of Combination HIV Prevention Interventions

Wellcome Trust

FWCI

0.86

Citation Percentile

0.7%

Citation Trend

2024

2025

2026

goldLicense: cc-by

journalhttps://doi.org/10.1128/spectrum.01251-23

publisherhttps://doi.org/10.1128/spectrum.01251-23

publisherhttps://journals.asm.org/doi/pdf/10.1128/spectrum.01251-23

repositoryhttps://pubmed.ncbi.nlm.nih.gov/37823653

repositoryhttps://www.ncbi.nlm.nih.gov/pmc/articles/10714836

Fields of Study

HIV Research and TreatmentHIV/AIDS Research and InterventionsHIV/AIDS drug development and treatment0303 health sciences03 medical and health sciencesHumansHIV-1Anti-HIV AgentsBotswanaDrug Resistance, ViralAnti-Retroviral AgentsHIV InfectionsMutationGenotypeOrganophosphatesPiperazines

MeSH Terms

BotswanaGenotypeHumansMutationOrganophosphatesPiperazinesHIV-1HIV InfectionsAnti-HIV AgentsDrug Resistance, ViralAnti-Retroviral Agents

Keywords

CohortHuman immunodeficiency virus (HIV)MedicineResistance (ecology)Cohort studyDemographyGeneticsInternal medicineVirologyBiologyPolymorphismsBotswanaEntry InhibitorsHiv-1 CDrug-resistant Mutations (Drms)Fostemsavir (Ftr)GenotypeAnti-HIV AgentsHIV InfectionsMicrobiologyQR1-502OrganophosphatesPiperazinesAnti-Retroviral AgentsDrug Resistance, ViralMutationHIV-1HumansResearch Article

Sustainable Development Goals

SDG 0: Good health and well-being