🏆 Finalist — NIH Data Sharing Index (“S-Index”) Challenge
Pilot corpus: NIH-funded biomedical datasets. Any DOI can be scored on demand — network effects sharpen as coverage grows.

Phase II trial of nivolumab and metformin in patients with treatment-refractory microsatellite stable metastatic colorectal cancer

Journal for ImmunoTherapy of Cancer(2023)10.1136/jitc-2023-007235Source: DataRank Database

Phase II trial of nivolumab and metformin in patients with treatment-refractory microsatellite stable metastatic colorectal cancer is a research paper published in Journal for ImmunoTherapy of Cancer (2023). On theSindex it has a DataRank of 1.0. It has been cited 45 times, with 45 citing works in its 1-hop citation network.

N/A
1.0DataRank · unranked

Scored on demand from live citation data

Deposits data Open Access45 citations · 45 citing works in its network
Download PDF
Cite:

Linked data & code

nct doi
Data availability

Repositories this paper deposited data in (declared in PubMed).

DataRank reads this dataset's downstream impact straight off the citation graph — no black box, no proprietary weighting. How is this computed?

Methodology & internals
datarank_citation_only_1hop_v6· scope data_onlyMethodology
Pipeline:MetadataData-paper checkEnrichmentCitation networkScoring
Enrichment:Funding (4 grants)OA: goldTopics (29)IDs (PubMed, PMC)Annotations (2)

FAIR Checklist

Context only (not used in score)
Findable (1/2)
  • Has DOI
Accessible (1/2)
  • Open Access
Interoperable (0/2)
    Reusable (0/3)

      FAIR checklist signals are shown for context only and do not affect DataRank scoring.

      Run a calibrated FAIR evaluation for this paper →

      We only score data papers we can read in full — never from an abstract alone.

      DataRank Breakdown

      Base Score 55%Citation Network 45%

      Base Score Contribution

      0.574

      From this paper's citation signal

      Citation Network Contribution

      0.468

      From 30 citing papers with measurable signal

      Learn more about DataRank methodology →

      Top 5 citers driving the network score

      Ranked by each citer's contribution to N(p) — log1p(Cq) divided by its reference count — out of 45 citers.

      1. CD47 as a potential predictive biomarker in colorectal cancer
        Journal for ImmunoTherapy of Cancer20253 citations19 referencesContributes 0.073
      2. Clinical evidence for the prognostic impact of metformin in cancer patients treated with immune checkpoint inhibitors
        International Immunopharmacology202411 citations61 referencesContributes 0.041
      3. Hypoxia is linked to acquired resistance to immune checkpoint inhibitors in lung cancer
        The Journal of Experimental Medicine202424 citations87 referencesContributes 0.037
      4. Metformin in Colorectal Cancer: Epidemiological Evidence, Predictive Biomarkers, and Implications for Prevention and Treatment
        International Journal of Molecular Sciences20259 citations70 referencesContributes 0.033
      5. Mitochondrial transfer at the crossroads of cancer, stromal, and immune cells
        Trends in Cell Biology20258 citations70 referencesContributes 0.031
      Live enrichment

      Bristol-Myers Squibb

      Grant: N/A

      Winship Cancer Institute of Emory University

      Grant: P30CA138292

      NCI NIH HHS

      Grant: P30 CA013148

      National Institutes of Health

      Grant: 5P30CA138292-11

      Winship Cancer Institute Cancer Center Support Grant

      Fields of Study

      03 medical and health sciences0302 clinical medicine

      MeSH Terms

      HumansColorectal NeoplasmsMetforminMicrosatellite RepeatsMiddle AgedFemaleMaleTumor MicroenvironmentProgrammed Cell Death 1 ReceptorNivolumab

      Keywords

      ImmunotherapyDrug therapy, CombinationTranslational Medical ResearchClinical Trials, Phase Ii As TopicClinical/Translational Cancer ImmunotherapyMaleProgrammed Cell Death 1 ReceptorNeoplasms. Tumors. Oncology. Including cancer and carcinogensMiddle AgedMetforminNivolumabTumor MicroenvironmentHumansFemaleColorectal NeoplasmsRC254-282Microsatellite Repeats

      Related Papers (10)

      Nature Communications(2021)
      co-cited
      10.1038/s41467-021-21246-9
      Nature Biotechnology(2015)
      co-cited
      10.1038/nbt.3192